Title : Akt kinases in breast cancer and the results of adjuvant therapy.

Pub. Date : 2003

PMID : 12631397






2 Functional Relationships(s)
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1 Patients with a negative status of Akt (no overexpression of Akt1, Akt2 or pAkt) showed significant benefit from tamoxifen. Tamoxifen AKT serine/threonine kinase 1 Homo sapiens
2 The relative rate of distant recurrence, with versus without tamoxifen, was 0.44 (95% confidence interval [CI], 0.25-0.79) for ER+/Akt1- patients, while it was 0.72 (95% CI, 0.34-1.53) for ER+/Akt1+ patients. Tamoxifen AKT serine/threonine kinase 1 Homo sapiens