Pub. Date : 2005 Oct
PMID : 16088978
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | AKT activation predicts outcome in breast cancer patients treated with tamoxifen. | Tamoxifen | AKT serine/threonine kinase 1 | Homo sapiens |
2 | The present study was carried out to test the hypothesis that AKT activation mediates tamoxifen resistance in clinical breast cancer. | Tamoxifen | AKT serine/threonine kinase 1 | Homo sapiens |
3 | The data presented here show that the PI3K/AKT/mTOR pathway is associated with relapse and death in ERalpha-positive breast cancer patients treated with tamoxifen, supporting in vitro evidence that AKT mediates tamoxifen resistance. | Tamoxifen | AKT serine/threonine kinase 1 | Homo sapiens |
4 | The data presented here show that the PI3K/AKT/mTOR pathway is associated with relapse and death in ERalpha-positive breast cancer patients treated with tamoxifen, supporting in vitro evidence that AKT mediates tamoxifen resistance. | Tamoxifen | AKT serine/threonine kinase 1 | Homo sapiens |
5 | The data presented here show that the PI3K/AKT/mTOR pathway is associated with relapse and death in ERalpha-positive breast cancer patients treated with tamoxifen, supporting in vitro evidence that AKT mediates tamoxifen resistance. | Tamoxifen | AKT serine/threonine kinase 1 | Homo sapiens |
6 | The data presented here show that the PI3K/AKT/mTOR pathway is associated with relapse and death in ERalpha-positive breast cancer patients treated with tamoxifen, supporting in vitro evidence that AKT mediates tamoxifen resistance. | Tamoxifen | AKT serine/threonine kinase 1 | Homo sapiens |