Title : Fine-tuning the intensity of the PKB/Akt signal enables diverse physiological responses.

Pub. Date : 2014

PMID : 25485494






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Both PDK1 and PKB can interact at the plasma membrane with a phosphoinositide synthesized by PI3K, the second messenger PtdIns(3,4,5)P3, enabling PDK1 to phosphorylate and activate PKB. phosphatidylinositol 3,4,5-triphosphate thymoma viral proto-oncogene 1 Mus musculus
2 Both PDK1 and PKB can interact at the plasma membrane with a phosphoinositide synthesized by PI3K, the second messenger PtdIns(3,4,5)P3, enabling PDK1 to phosphorylate and activate PKB. phosphatidylinositol 3,4,5-triphosphate thymoma viral proto-oncogene 1 Mus musculus