Title : Arachidonoyl-phosphatidylcholine oscillates during the cell cycle and counteracts proliferation by suppressing Akt membrane binding.

Pub. Date : 2013 Feb 12

PMID : 23359699






1 Functional Relationships(s)
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1 Additive effects of 20:4-PC and LY294002 were not observed, underlining the critical role of Akt for 20:4-PC signaling; 20:4-PC suppressed Akt membrane translocation as shown by immunofluorescence microscopy but left the concentration of the anchor lipid phosphatidylinositol-3,4,5-trisphosphate unchanged. phosphatidylinositol 3,4,5-triphosphate thymoma viral proto-oncogene 1 Mus musculus