Pub. Date : 2014
PMID : 24392697
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | One of the most studied tumor suppressors in these pathways is the lipid phosphatase PTEN (phosphatase and tensin homolog deleted on chromosome ten), which dephosphorylates the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate (PIP3), thus preventing activation of the oncogenic kinase AKT (v-akt murine thymoma viral oncogene homolog). | phosphatidylinositol 3,4,5-triphosphate | thymoma viral proto-oncogene 1 | Mus musculus |