Title : PTEN action in leukaemia dictated by the tissue microenvironment.

Pub. Date : 2014 Jun 19

PMID : 24805236






1 Functional Relationships(s)
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Protein Name
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1 PTEN dephosphorylates phosphatidylinositol (3,4,5)-triphosphate, thereby opposing the activity of class I phosphatidylinositol 3-kinases that mediate growth- and survival-factor signalling through phosphatidylinositol 3-kinase effectors such as AKT and mTOR. phosphatidylinositol 3,4,5-triphosphate thymoma viral proto-oncogene 1 Mus musculus