Title : Involvement of the phosphoinositide 3-kinase/protein kinase B signaling pathway in insulin/IGF-I-induced chondrogenesis of the mouse embryonal carcinoma-derived cell line ATDC5.

Pub. Date : 2001 Nov

PMID : 11551825






1 Functional Relationships(s)
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1 ATDC5 cells produced phosphatidylinositol 3,4,5-trisphosphate and the pleckstrin homology domain of PKB was recruited to the plasma membrane in response to insulin stimulation. phosphatidylinositol 3,4,5-triphosphate thymoma viral proto-oncogene 1 Mus musculus