| 1 |
35198877 | SARM1 is a multi-functional NAD(P)ase with prominent base exchange activity, all regulated bymultiple physiologically relevant NAD metabolites. | 2022 Feb 18 |
2 |
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35493328 | SARM1 Depletion Slows Axon Degeneration in a CNS Model of Neurotropic Viral Infection. | 2022 |
1 |
| 3 |
33129841 | Vincristine- and bortezomib-induced neuropathies - from bedside to bench and back. | 2021 Feb |
1 |
| 4 |
33468661 | Multiple domain interfaces mediate SARM1 autoinhibition. | 2021 Jan 26 |
3 |
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33831359 | An NAD+/NMN balancing act by SARM1 and NMNAT2 controls axonal degeneration. | 2021 Apr 7 |
3 |
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34175654 | SARM1 signaling mechanisms in the injured nervous system. | 2021 Aug |
1 |
| 7 |
34213829 | Acidic pH irreversibly activates the signaling enzyme SARM1. | 2021 Dec |
1 |
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34302821 | Risks and rewards of targeting NAD+ homeostasis in the brain. | 2021 Sep |
1 |
| 9 |
34307460 | A Novel NAD Signaling Mechanism in Axon Degeneration and its Relationship to Innate Immunity. | 2021 |
1 |
| 10 |
34403688 | Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection. | 2021 Nov |
17 |
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34455132 | SARM1-mediated wallerian degeneration: A possible mechanism underlying organophosphorus-induced delayed neuropathy. | 2021 Oct |
1 |
| 12 |
34509469 | The balance between NAD+ biosynthesis and consumption in ageing. | 2021 Oct |
1 |
| 13 |
34870595 | Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1. | 2021 Dec 6 |
2 |
| 14 |
34871367 | NAD+-consuming enzymes in immune defense against viral infection. | 2021 Dec 10 |
1 |
| 15 |
32049506 | Initial Kinetic Characterization of Sterile Alpha and Toll/Interleukin Receptor Motif-Containing Protein 1. | 2020 Mar 3 |
2 |
| 16 |
32087251 | cADPR is a gene dosage-sensitive biomarker of SARM1 activity in healthy, compromised, and degenerating axons. | 2020 Jul |
4 |
| 17 |
32311648 | The SARM1 axon degeneration pathway: control of the NAD+ metabolome regulates axon survival in health and disease. | 2020 Aug |
1 |
| 18 |
32755591 | Structural and Mechanistic Regulation of the Pro-degenerative NAD Hydrolase SARM1. | 2020 Aug 4 |
1 |
| 19 |
32828421 | Identification of the first noncompetitive SARM1 inhibitors. | 2020 Sep 15 |
1 |
| 20 |
33053563 | The NAD+-mediated self-inhibition mechanism of pro-neurodegenerative SARM1. | 2020 Dec |
2 |
| 21 |
33185189 | Structural basis for SARM1 inhibition and activation under energetic stress. | 2020 Nov 13 |
4 |
| 22 |
30633870 | SARM: From immune regulator to cell executioner. | 2019 Mar |
2 |
| 23 |
31128467 | A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death. | 2019 May 31 |
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| 24 |
31278906 | Structural Evidence for an Octameric Ring Arrangement of SARM1. | 2019 Sep 6 |
2 |
| 25 |
31439792 | NAD+ cleavage activity by animal and plant TIR domains in cell death pathways. | 2019 Aug 23 |
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| 26 |
31439793 | TIR domains of plant immune receptors are NAD+-cleaving enzymes that promote cell death. | 2019 Aug 23 |
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| 27 |
29395922 | TIR Domain Proteins Are an Ancient Family of NAD+-Consuming Enzymes. | 2018 Feb 5 |
2 |
| 28 |
30257945 | Pharmacological bypass of NAD+ salvage pathway protects neurons from chemotherapy-induced degeneration. | 2018 Oct 16 |
2 |
| 29 |
30333228 | c-Jun N-terminal kinase (JNK)-mediated phosphorylation of SARM1 regulates NAD+ cleavage activity to inhibit mitochondrial respiration. | 2018 Dec 7 |
3 |
| 30 |
28095293 | MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2. | 2017 Jan 17 |
2 |
| 31 |
28334607 | The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD+ Cleavage Activity that Promotes Pathological Axonal Degeneration. | 2017 Mar 22 |
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