Title : Initial Kinetic Characterization of Sterile Alpha and Toll/Interleukin Receptor Motif-Containing Protein 1.

Pub. Date : 2020 Mar 3

PMID : 32049506






2 Functional Relationships(s)
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1 Recently, SARM1 was shown to promote neurodegeneration via its ability to hydrolyze NAD+, forming nicotinamide and ADP ribose (ADPR). NAD sterile alpha and TIR motif containing 1 Homo sapiens
2 Finally, we show that the SARM1 hydrolyzes NAD+ via an ordered uni-bi reaction in which nicotinamide is released prior to ADPR. NAD sterile alpha and TIR motif containing 1 Homo sapiens