Title : An NAD+/NMN balancing act by SARM1 and NMNAT2 controls axonal degeneration.

Pub. Date : 2021 Apr 7

PMID : 33831359






3 Functional Relationships(s)
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1 An NAD+/NMN balancing act by SARM1 and NMNAT2 controls axonal degeneration. NAD sterile alpha and TIR motif containing 1 Homo sapiens
2 (2021) reveal a key regulatory mechanism that controls SARM1"s enzymatic activity, providing insight into how NAD+ biosynthesis by the NMNAT2 enzyme protects axons, and a new therapeutic path to tune SARM1 activity. NAD sterile alpha and TIR motif containing 1 Homo sapiens
3 (2021) reveal a key regulatory mechanism that controls SARM1"s enzymatic activity, providing insight into how NAD+ biosynthesis by the NMNAT2 enzyme protects axons, and a new therapeutic path to tune SARM1 activity. NAD sterile alpha and TIR motif containing 1 Homo sapiens