Pub. Date : 2019 Mar
PMID : 30633870
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | SARM has been shown to deplete NAD+ by possessing intrinsic NADase activity in the TIR domain of the protein. | NAD | sterile alpha and TIR motif containing 1 | Homo sapiens |
| 2 | It is thought that this activity of SARM is normally switched off by the axo-protective activities of NMNAT2 which maintain low levels of the NAD+ precursor NMN. | NAD | sterile alpha and TIR motif containing 1 | Homo sapiens |