Title : TIR domains of plant immune receptors are NAD+-cleaving enzymes that promote cell death.

Pub. Date : 2019 Aug 23

PMID : 31439793






2 Functional Relationships(s)
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Protein Name
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1 Both cell death induction and NAD+ cleavage activity of plant TIR domains require known self-association interfaces and a putative catalytic glutamic acid that is conserved in both bacterial TIR NAD+-cleaving enzymes (NADases) and the mammalian SARM1 (sterile alpha and TIR motif containing 1) NADase. NAD sterile alpha and TIR motif containing 1 Homo sapiens
2 Both cell death induction and NAD+ cleavage activity of plant TIR domains require known self-association interfaces and a putative catalytic glutamic acid that is conserved in both bacterial TIR NAD+-cleaving enzymes (NADases) and the mammalian SARM1 (sterile alpha and TIR motif containing 1) NADase. NAD sterile alpha and TIR motif containing 1 Homo sapiens