Title : Structural and Mechanistic Regulation of the Pro-degenerative NAD Hydrolase SARM1.

Pub. Date : 2020 Aug 4

PMID : 32755591

1 Functional Relationships(s)
Compound Name
Protein Name
1 Notably, the mutants cannot be further activated by the endogenous activator nicotinamide mononucleotide (NMN), and active SARM1 is product inhibited by Nicotinamide (NAM), highlighting SARM1"s functional dependence on key metabolites in the NAD salvage pathway. NAD sterile alpha and TIR motif containing 1 Homo sapiens