Title : Vincristine- and bortezomib-induced neuropathies - from bedside to bench and back.

Pub. Date : 2021 Feb

PMID : 33129841

1 Functional Relationships(s)
Compound Name
Protein Name
1 Axon degeneration following both vincristine and bortezomib is mediated by a phylogenetically ancient, genetically encoded axon destruction program that leads to the activation of the Toll-like receptor adaptor SARM1 (sterile alpha and TIR motif containing protein 1) and local decrease of nicotinamide dinucleotide (NAD+). NAD sterile alpha and TIR motif containing 1 Homo sapiens