Dasatinib

ABL proto-oncogene 1, non-receptor tyrosine kinase ; Homo sapiens







407 Article(s)
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101 30167550 Tyrosine Kinase Inhibitors in Pulmonary Vascular Disease. 2016 Dec 1
102 25025538 Spontaneous subdural hematoma in a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia with normal platelet count after dasatinib treatment. 2015 1
103 25179732 Relapse of BCR-ABL1-like ALL mediated by the ABL1 kinase domain mutation T315I following initial response to dasatinib treatment. 2015 Jan 2
104 25351958 The clinically approved drugs dasatinib and bosutinib induce anti-inflammatory macrophages by inhibiting the salt-inducible kinases. 2015 Jan 15 2
105 25499760 Janus kinase inhibition by ruxolitinib extends dasatinib- and dexamethasone-induced remissions in a mouse model of Ph+ ALL. 2015 Feb 26 1
106 25526365 A sensitive and microscale method for drug screening combining affinity probes and single molecule fluorescence correlation spectroscopy. 2015 Feb 21 2
107 25831762 [Inhibitors for ABL, KIT and PDGFR tyrosine kinases--imatinib, nitotinib, and dasatinib]. 2015 Feb 1
108 25842192 Reactivation of resolved infection with the hepatitis B virus immune escape mutant G145R during dasatinib treatment for chronic myeloid leukemia. 2015 Sep 1
109 25889792 The transcription factor MITF is a critical regulator of GPNMB expression in dendritic cells. 2015 Mar 24 1
110 25913326 A thirty-five nucleotides BCR-ABL1 insertion mutation of controversial significance confers resistance to imatinib in a patient with chronic myeloid leukemia (CML). 2015 Aug 1
111 25996455 Small-world networks of residue interactions in the Abl kinase complexes with cancer drugs: topology of allosteric communication pathways can determine drug resistance effects. 2015 Jul 2
112 26284693 Clinical features of pulmonary arterial hypertension in patients receiving dasatinib. 2015 Nov 1
113 26430722 Concomitant JAK2 V617F-positive polycythemia vera and BCR-ABL-positive chronic myelogenous leukemia treated with ruxolitinib and dasatinib. 2015 Oct 2 1
114 26473951 Knockout Serum Replacement Promotes Cell Survival by Preventing BIM from Inducing Mitochondrial Cytochrome C Release. 2015 1
115 26588899 Dasatinib blocks transcriptional and promigratory responses to transforming growth factor-beta in pancreatic adenocarcinoma cells through inhibition of Smad signalling: implications for in vivo mode of action. 2015 Nov 21 1
116 23989453 A screening-based approach to circumvent tumor microenvironment-driven intrinsic resistance to BCR-ABL+ inhibitors in Ph+ acute lymphoblastic leukemia. 2014 Jan 1
117 24143950 BCR-ABL inhibitors: updates in the management of patients with chronic-phase chronic myeloid leukemia. 2014 Jul 1
118 24258348 Ever-advancing chronic myeloid leukemia treatment. 2014 Feb 1
119 24311723 Early response with dasatinib or imatinib in chronic myeloid leukemia: 3-year follow-up from a randomized phase 3 trial (DASISION). 2014 Jan 23 1
120 24569263 Long-term outcome with dasatinib after imatinib failure in chronic-phase chronic myeloid leukemia: follow-up of a phase 3 study. 2014 Apr 10 1
121 24569990 Inhibiting tyrosine phosphorylation of protein kinase Cδ (PKCδ) protects the salivary gland from radiation damage. 2014 Apr 11 1
122 24734217 Dasatinib promotes the expansion of a therapeutically superior T-cell repertoire in response to dendritic cell vaccination against melanoma. 2014 Jan 1 1
123 24756784 Dasatinib. 2014 3
124 24847647 New resistance mechanisms for small molecule kinase inhibitors of Abl kinase. 2014 Mar 1
125 24882272 Dasatinib enhances migration of monocyte-derived dendritic cells by reducing phosphorylation of inhibitory immune receptors Siglec-9 and Siglec-3. 2014 Sep 1
126 24975338 [Successful treatment with dasatinib for polycythemia vera patient emerging BCR-ABL positive clone during 13 years of treatment]. 2014 Jun 1
127 25006277 Importance of early and deeper responses to long-term survival in CML patients: Implications of BCR-ABL testing in management of CML in Indian setting. 2014 Jan 1
128 25023728 Combined SFK/mTOR inhibition prevents rapamycin-induced feedback activation of AKT and elicits efficient tumor regression. 2014 Sep 1 1
129 25068103 Identification of a novel SEPT9-ABL1 fusion gene in a patient with T-cell prolymphocytic leukemia. 2014 1
130 25114223 Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells. 2014 Aug 26 1
131 25173530 Sensitive methods for detection of the S768R substitution in exon 18 of the DDR2 gene in patients with central nervous system metastases of non-small cell lung cancer. 2014 Oct 1
132 25193862 Overcoming EMT-associated resistance to anti-cancer drugs via Src/FAK pathway inhibition. 2014 Sep 15 1
133 25198091 Real-time analysis of imatinib- and dasatinib-induced effects on chronic myelogenous leukemia cell interaction with fibronectin. 2014 1
134 25207766 Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia. 2014 Sep 11 1
135 25284075 Reduced miR-3127-5p expression promotes NSCLC proliferation/invasion and contributes to dasatinib sensitivity via the c-Abl/Ras/ERK pathway. 2014 Oct 6 2
136 25331939 Combination therapy with nilotinib for drug-sensitive and drug-resistant BCR-ABL-positive leukemia and other malignancies. 2014 Dec 1
137 25426931 Inhibition of Aurora kinase B is important for biologic activity of the dual inhibitors of BCR-ABL and Aurora kinases R763/AS703569 and PHA-739358 in BCR-ABL transformed cells. 2014 1
138 25501110 Efficacy of molecular response at 1 or 3 months after the initiation of dasatinib treatment can predict an improved response to dasatinib in imatinib-resistant or imatinib-intolerant Japanese patients with chronic myelogenous leukemia during the chronic phase. 2014 4
139 25584281 Diffuse hypopigmentation followed by hyperpigmentation in an african american woman with hemangiopericytoma treated with dasatinib. 2014 Nov 1
140 22392508 Phase I trial of dasatinib and ixabepilone in patients with solid tumors. 2013 Feb 1
141 23053188 Impact of BCR-ABL mutations on response to dasatinib after imatinib failure in elderly patients with chronic-phase chronic myeloid leukemia. 2013 Jan 2
142 23065514 The quantitative level of T315I mutated BCR-ABL predicts for major molecular response to second-line nilotinib or dasatinib treatment in patients with chronic myeloid leukemia. 2013 May 1
143 23065516 Dasatinib targets chronic myeloid leukemia-CD34+ progenitors as effectively as it targets mature cells. 2013 Jun 1
144 23233201 PECAM-1 is involved in BCR/ABL signaling and may downregulate imatinib-induced apoptosis of Philadelphia chromosome-positive leukemia cells. 2013 Feb 2
145 23247657 The synthesis of Bcr-Abl inhibiting anticancer pharmaceutical agents imatinib, nilotinib and dasatinib. 2013 Mar 21 2
146 23299860 Molecular subtype and response to dasatinib, an Src/Abl small molecule kinase inhibitor, in hepatocellular carcinoma cell lines in vitro. 2013 May 2
147 23372106 Treating chronic myeloid leukemia: improving management through understanding of the patient experience. 2013 Feb 2
148 23383600 Surrogate end points for long-term outcomes in chronic myeloid leukemia. 2013 Oct 1
149 23409026 Sensitive detection of pre-existing BCR-ABL kinase domain mutations in CD34+ cells of newly diagnosed chronic-phase chronic myeloid leukemia patients is associated with imatinib resistance: implications in the post-imatinib era. 2013 2
150 23420553 Apoptosis in chronic myeloid leukemia cells transiently treated with imatinib or dasatinib is caused by residual BCR-ABL kinase inhibition. 2013 May 1