Dasatinib

ABL proto-oncogene 1, non-receptor tyrosine kinase ; Homo sapiens







407 Article(s)
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1 35092492 Combination of dasatinib and okadaic acid induces apoptosis and cell cycle arrest by targeting protein phosphatase PP2A in chronic myeloid leukemia cells. 2022 Jan 29 1
2 35164068 2-Hydroxyestradiol Overcomes Mesenchymal Stem Cells-Mediated Platinum Chemoresistance in Ovarian Cancer Cells in an ERK-Independent Fashion. 2022 Jan 26 1
3 35256549 Dasatinib-induced reversible pulmonary arterial hypertension in a pediatric patient with BCR/ABL1+ lymphoblastic lymphoma from chronic myeloid leukemia. 2022 Mar 31 1
4 35402127 Effective collaboration between hematologists and cardiologists facilitated successful control of reversible dasatinib-related pulmonary arterial hypertension and treatment-free remission of chronic myeloid leukemia: a case report. 2022 Apr 1
5 35550008 Loss of cAbl Tyrosine Kinase in Pulmonary Arterial Hypertension Causes Dysfunction of Vascular Endothelial Cells. 2022 May 13 1
6 35551463 BCR::ABL1 tyrosine kinase inhibitors hamper the therapeutic efficacy of blinatumomab in vitro. 2022 May 13 1
7 33155931 Effect of Dasatinib on Genes Related to Mitotic Catastrophe Pathway in Chronic Myeloid Leukemia Cells. 2021 1
8 33376671 Successful treatment with ABL tyrosine kinase inhibitor for patients with acute myeloid leukemia with BCR-ABL1. 2021 1
9 33390067 In-vitro modeling of TKI resistance in the high-risk B-cell acute lymphoblastic leukemia fusion gene RANBP2-ABL1 - implications for targeted therapy. 2021 May 1
10 33407162 Differential gene expression analysis of dasatinib-induced colitis in a patient with chronic myeloid leukemia followed for 3 years: a case report. 2021 Jan 6 1
11 33748144 The Discovery of Novel BCR-ABL Tyrosine Kinase Inhibitors Using a Pharmacophore Modeling and Virtual Screening Approach. 2021 1
12 33772839 High-throughput liquid chromatography/electrospray ionization-tandem mass spectrometry method using in-source collision-induced dissociation for simultaneous quantification of imatinib, dasatinib, bosutinib, nilotinib, and ibrutinib in human plasma. 2021 Aug 1
13 33814500 BCR/ABL1-positive B-lymphoblastic Lymphoma Successfully Treated with Dasatinib-combined Chemotherapy. 2021 Oct 1 2
14 33976882 Dasatinib-induced chylothorax in a patient with chronic myeloid leukaemia: a case report and literature review. 2021 Jun 1
15 34054462 A Case Report of BCR-ABL-JAK2-Positive Chronic Myeloid Leukemia with Complete Hematological and Major Molecular Response to Dasatinib. 2021 Jan-Apr 2
16 34195988 Dasatinib dose optimisation based on therapeutic drug monitoring reduces pleural effusion rates in chronic myeloid leukaemia patients. 2021 Jul 1
17 34276365 Impact of the Breakpoint Region on the Leukemogenic Potential and the TKI Responsiveness of Atypical BCR-ABL1 Transcripts. 2021 1
18 34433624 KIR3DL1 Allotype-Dependent Modulation of NK Cell Immunity against Chronic Myeloid Leukemia. 2021 Aug 25 1
19 34599372 Investigation on the interaction behavior of afatinib, dasatinib, and imatinib docked to the BCR-ABL protein. 2021 Oct 1 1
20 34830455 Perturbation of p38α MAPK as a Novel Strategy to Effectively Sensitize Chronic Myeloid Leukemia Cells to Therapeutic BCR-ABL Inhibitors. 2021 Nov 22 1
21 31688632 Dasatinib-induced Chylothorax in Chronic Myelogenous Leukemia in Pediatric Patient: Report of a Case and Review of Literature. 2020 Oct 1
22 32094501 Innate T-αβ lymphocytes as new immunological components of anti-tumoral "off-target" effects of the tyrosine kinase inhibitor dasatinib. 2020 Feb 24 1
23 32248338 Dasatinib-induced chylothorax: report of a case and review of the literature. 2020 Oct 1
24 32266142 Rapid Molecular Response to Dasatinib in a Pediatric Relapsed Acute Lymphoblastic Leukemia With NCOR1-LYN Fusion. 2020 1
25 32279331 Response to tyrosine kinase inhibitors in myeloid neoplasms associated with PCM1-JAK2, BCR-JAK2 and ETV6-ABL1 fusion genes. 2020 Jul 1
26 32340449 In Situ Study of the Drug-Target Protein Interaction in Single Living Cells by Combining Fluorescence Correlation Spectroscopy with Affinity Probes. 2020 May 19 1
27 32424388 Is breaking of a hydrogen bond enough to lead to drug resistance? 2020 Jun 18 1
28 32536651 Dasatinib-induced Nonspecific Interstitial Pneumonia That Developed 7 Years after the Initiation of Dasatinib. 2020 Sep 15 2
29 32568522 A Nimbolide-Based Kinase Degrader Preferentially Degrades Oncogenic BCR-ABL. 2020 Jul 17 4
30 32654459 [Variables associated with BCR-ABL kinase domain mutation in TKI-resistant patients with chronic myeloid leukemia]. 2020 Jun 14 3
31 32667912 Inhibition of ABL1 tyrosine kinase reduces HTLV-1 proviral loads in peripheral blood mononuclear cells from patients with HTLV-1-associated myelopathy/tropical spastic paraparesis. 2020 Jul 1
32 32879093 Combination of axitinib with dasatinib improves the outcome of a chronic myeloid leukemia patient with BCR-ABL1 T315I mutation. 2020 Jul 28 2
33 33074527 Precision medicine in acute lymphoblastic leukemia. 2020 Dec 1
34 33291786 Activity-Based Protein Profiling Reveals Potential Dasatinib Targets in Gastric Cancer. 2020 Dec 4 1
35 30093398 Incidence, outcomes, and risk factors of pleural effusion in patients receiving dasatinib therapy for Philadelphia chromosome-positive leukemia. 2019 Jan 1
36 30332954 Chronic Myeloid Leukemia: Existing Therapeutic Options and Strategies to Overcome Drug Resistance. 2019 1
37 30546081 Optimized induction of mitochondrial apoptosis for chemotherapy-free treatment of BCR-ABL+acute lymphoblastic leukemia. 2019 Jun 1
38 30568173 Dasatinib and navitoclax act synergistically to target NUP98-NSD1+/FLT3-ITD+ acute myeloid leukemia. 2019 Jun 2
39 30879266 Pre- and post-transplant ponatinib for a patient with acute megakaryoblastic blast phase chronic myeloid leukemia with T315I mutation who underwent allogeneic hematopoietic stem cell transplantation. 2019 Jul 1
40 30956968 Coexistence of BCR/ABL1-positive chronic myeloid leukemia and JAK2 V617F-mutated myelofibrosis successfully treated with dasatinib and ruxolitinib. 2019 Mar 1
41 30971653 [The mechanisms of taxodione-induced apoptosis in BCR-ABL-positive leukemia cells]. 2019 1
42 31014138 Response to single agent dasatinib post allogeneic transplant in B-cell acute lymphoblastic leukemia with NUP214-ABL1. 2019 Nov 1
43 31539241 Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. 2019 Oct 24 1
44 28554234 Molecular characterization and therapeutic reaction to dasatinib in a CML patient harboring a novel e8a2 BCR-ABL1 transcript with a somatic mutation in TP53BP2 and cadherin-10 genes. 2018 Jan 1
45 29035389 'MCC' protein interacts with E-cadherin and β-catenin strengthening cell-cell adhesion of HCT116 colon cancer cells. 2018 Feb 1 1
46 29315500 Long-term outcome of dasatinib first-line treatment in gastrointestinal stromal tumor: A multicenter, 2-stage phase 2 trial (Swiss Group for Clinical Cancer Research 56/07). 2018 Apr 1 1
47 29336809 Screening of break point cluster region Abelson tyrosine kinase inhibitors by capillary electrophoresis. 2018 Feb 16 1
48 29434033 PDGFRB mutation and tyrosine kinase inhibitor resistance in Ph-like acute lymphoblastic leukemia. 2018 May 17 1
49 29464092 mTOR inhibition enhances efficacy of dasatinib in ABL-rearranged Ph-like B-ALL. 2018 Jan 19 3
50 29541231 Co-existence of isodicentric Ph chromosomes and the three-way Ph chromosome variant t(3;9;22)(p21;q34;q11) in a rare case of chronic myeloid leukemia. 2018 Apr 1