Dasatinib

ABL proto-oncogene 1, non-receptor tyrosine kinase ; Homo sapiens







407 Article(s)
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51 29549929 Local Anesthetic Drug Inhibits Growth and Survival in Chronic Myeloid Leukemia Through Suppressing PI3K/Akt/mTOR. 2018 Mar 2
52 29551130 Acquired Resistance to Drugs Targeting Tyrosine Kinases. 2018 1
53 29902613 Dasatinib sensitises KRAS-mutant cancer cells to mitogen-activated protein kinase kinase inhibitor via inhibition of TAZ activity. 2018 Aug 1
54 29937990 Targeting autophagy sensitises lung cancer cells to Src family kinase inhibitors. 2018 Jun 8 1
55 29945329 Interferon-α Based Individualized Treatment of a High Risk Chronic Myelogenous Leukemia Patient Harboring T315I Mutation. 2018 Jun 1 2
56 30024740 Multiplexed Quantitative MALDI MS Approach for Assessing Activity and Inhibition of Protein Kinases Based on Postenrichment Dephosphorylation of Phosphopeptides by Metal-Organic Framework-Templated Porous CeO2. 2018 Aug 21 1
57 30069624 Dasatinib. 2018 3
58 30202081 Pharmacological difference between degrader and inhibitor against oncogenic BCR-ABL kinase. 2018 Sep 10 2
59 30217442 BCR-ABL tyrosine kinase inhibition induces metabolic vulnerability by preventing the integrated stress response in K562 cells. 2018 Oct 12 1
60 30301525 Antibiotic anisomycin selectively targets leukemia cell lines and patient samples through suppressing Wnt/β-catenin signaling. 2018 Nov 2 1
61 30587121 Post-treatment de-phosphorylation of p53 correlates with dasatinib responsiveness in malignant melanoma. 2018 Dec 27 1
62 30616322 [Study on mechanism for dasatinib inhibiting PDGFR/Bcr-Abl signaling pathway in hepatic stellate cells mediated hepatic fibrosis]. 2018 Nov 20 1
63 30705677 NKG2A Down-Regulation by Dasatinib Enhances Natural Killer Cytotoxicity and Accelerates Effective Treatment Responses in Patients With Chronic Myeloid Leukemia. 2018 2
64 27777238 Potent efficacy of combined PI3K/mTOR and JAK or ABL inhibition in murine xenograft models of Ph-like acute lymphoblastic leukemia. 2017 Jan 12 1
65 27848186 Dasatinib induces autophagy in mice with Bcr-Abl-positive leukemia. 2017 Mar 4
66 27852118 Risk of arterial and venous occlusive events in chronic myeloid leukemia patients treated with new generation BCR-ABL tyrosine kinase inhibitors: a systematic review and meta-analysis. 2017 Jan 1
67 28044939 Inhibition of TGF-β Signaling in Tumor Cells by Small Molecule Src Family Kinase Inhibitors. 2017 1
68 28213007 Effect of dasatinib on EMT-mediated-mechanism of resistance against EGFR inhibitors in lung cancer cells. 2017 Feb 1
69 28245378 [Effects of PCI-32765 and Dasatinib on the Acute Lymphoblastic Leukemic Cells and Their Mechanisms]. 2017 Feb 2
70 28283735 In vitro and in vivo evaluation of dasatinib and imatinib on physiological parameters of pulmonary arterial hypertension. 2017 Apr 1
71 28349229 MPT0B002, a novel microtubule inhibitor, downregulates T315I mutant Bcr-Abl and induces apoptosis of imatinib-resistant chronic myeloid leukemia cells. 2017 Aug 1
72 28456613 E-Cadherin-Mediated Cell Contact Controls the Epidermal Damage Response in Radiation Dermatitis. 2017 Aug 1
73 28544567 Chemoproteomics-Aided Medicinal Chemistry for the Discovery of EPHA2 Inhibitors. 2017 Jun 21 1
74 28556300 Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. 2017 Aug 3
75 28599273 Targeting BCR-ABL+ stem/progenitor cells and BCR-ABL-T315I mutant cells by effective inhibition of the BCR-ABL-Tyr177-GRB2 complex. 2017 Jul 4 1
76 28622336 A knowledge-based T2-statistic to perform pathway analysis for quantitative proteomic data. 2017 Jun 1
77 28674529 Abl Tyrosine Kinase Regulates Hepatitis C Virus Entry. 2017 2
78 28743118 Disappearance of Bone Marrow Fibrosis in a Patient with Chronic Myeloid Leukemia Treated with Dasatinib. 2017 1
79 28749919 Philadelphia chromosome-like acute lymphoblastic leukemia: progress in a new cancer subtype. 2017 Jul 1
80 28821556 Dasatinib Reversibly Disrupts Endothelial Vascular Integrity by Increasing Non-Muscle Myosin II Contractility in a ROCK-Dependent Manner. 2017 Nov 1 1
81 29067094 Dasatinib and chemotherapy in a patient with early T-cell precursor acute lymphoblastic leukemia and NUP214-ABL1 fusion: A case report. 2017 Nov 8
82 29091939 Evaluation of the efficacy of dasatinib, a Src/Abl inhibitor, in colorectal cancer cell lines and explant mouse model. 2017 1
83 29127384 Targeting c-KIT (CD117) by dasatinib and radotinib promotes acute myeloid leukemia cell death. 2017 Nov 10 1
84 29256412 Nephrotic syndrome under treatment with dasatinib: be aware of a possible adverse drug reaction. 2017 Dec 1
85 29296813 Oncogenic role and therapeutic targeting of ABL-class and JAK-STAT activating kinase alterations in Ph-like ALL. 2017 Sep 12 3
86 26479578 In-silico identification of inhibitors against mutated BCR-ABL protein of chronic myeloid leukemia: a virtual screening and molecular dynamics simulation study. 2016 Oct 1
87 26507546 Pharmacokinetics and pharmacodynamics of dasatinib in the chronic phase of newly diagnosed chronic myeloid leukemia. 2016 Feb 1
88 26582603 Hyaluronan oligomers sensitize chronic myeloid leukemia cell lines to the effect of Imatinib. 2016 Apr 1
89 26802644 What Is the Optimal Dose and Schedule for Dasatinib in Chronic Myeloid Leukemia: Two Case Reports and Review of the Literature. 2016 Jan 21 1
90 26876246 [Dasatinib treatment based on BCR- ABL mutation detection in imatinib- resistant patients with chronic myeloid leukemia]. 2016 Jan 3
91 27044711 A role for FOXO1 in BCR-ABL1-independent tyrosine kinase inhibitor resistance in chronic myeloid leukemia. 2016 Jul 3
92 27078848 CRKL mediates EML4-ALK signaling and is a potential therapeutic target for ALK-rearranged lung adenocarcinoma. 2016 May 17 1
93 27347777 Deep molecular response by IFN-α and dasatinib combination in a patient with T315I-mutated chronic myeloid leukemia. 2016 Jul 1
94 27520370 Anthelmintic drug niclosamide enhances the sensitivity of chronic myeloid leukemia cells to dasatinib through inhibiting Erk/Mnk1/eIF4E pathway. 2016 Sep 16 1
95 27521332 Multiparameter Analysis of Off-Target Effects of Dasatinib on Bone Homeostasis in Patients With Newly Diagnosed Chronic Myelogenous Leukemia. 2016 Aug 1
96 27583255 Current status of ABL tyrosine kinase inhibitors stop studies for chronic myeloid leukemia. 2016 1
97 27636353 Fusion proteins in head and neck neoplasms: Clinical implications, genetics, and future directions for targeting. 2016 Oct 2 1
98 27656875 Dasatinib-Induced T-Cell-Mediated Colitis: A Case Report and Review of the Literature. 2016 1
99 27803756 Dasatinib-induced pleural effusion: Chylothorax, an option to consider. 2016 Oct-Dec 1
100 28191543 The third-time chronic myeloid leukemia in lymphoblastic crisis with ABL1 kinase mutation induced by decitabine, dexamethason combined with nilotinib and dasatinib. 2016 Dec 1 1