Title : Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia.

Pub. Date : 2014 Sep 11

PMID : 25207766






1 Functional Relationships(s)
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1 Cell lines and human leukemic cells expressing ABL1, ABL2, CSF1R, and PDGFRB fusions were sensitive in vitro to dasatinib, EPOR and JAK2 rearrangements were sensitive to ruxolitinib, and the ETV6-NTRK3 fusion was sensitive to crizotinib. Dasatinib ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens