Title : Inhibition of Aurora kinase B is important for biologic activity of the dual inhibitors of BCR-ABL and Aurora kinases R763/AS703569 and PHA-739358 in BCR-ABL transformed cells.

Pub. Date : 2014

PMID : 25426931






1 Functional Relationships(s)
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1 ABL tyrosine kinase inhibitors (TKI) like Imatinib, Dasatinib and Nilotinib are the gold standard in conventional treatment of CML. Dasatinib ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens