Guanosine Diphosphate

RAB5A, member RAS oncogene family ; Homo sapiens







45 Article(s)
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Title
Pub. Year
#Total Relationships
1 31811856 Roles of the G protein-coupled receptor kinase 2 and Rab5 in α1B-adrenergic receptor function and internalization. 2020 Jan 15 2
2 32104603 The Emerging Role of Rab5 in Membrane Receptor Trafficking and Signaling Pathways. 2020 1
3 33335690 Structure-based discovery of neoandrographolide as a novel inhibitor of Rab5 to suppress cancer growth. 2020 7
4 29065764 Recognition and stabilization of geranylgeranylated human Rab5 by the GDP Dissociation Inhibitor (GDI). 2019 May 3
5 31292193 Focal adhesion kinase-dependent activation of the early endocytic protein Rab5 is associated with cell migration. 2019 Aug 23 6
6 29743547 The Protease Activated Receptor2 Promotes Rab5a Mediated Generation of Pro-metastatic Microvesicles. 2018 May 9 3
7 28779233 Crystal structures of two forms of the Acanthamoeba polyphaga mimivirus Rab GTPase. 2017 Nov 2
8 28968219 Site-specific monoubiquitination downregulates Rab5 by disrupting effector binding and guanine nucleotide conversion. 2017 Oct 2 1
9 27335171 Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency. 2016 Sep 1 1
10 27841328 Single GDP-dissociation Inhibitor Protein regulates endocytic and secretory pathways in Leishmania. 2016 Nov 14 2
11 25753113 Fluorescence microscopy colocalization of lipid-nucleic acid nanoparticles with wildtype and mutant Rab5-GFP: A platform for investigating early endosomal events. 2015 Jun 1
12 25800849 Determination of Rab5 activity in the cell by effector pull-down assay. 2015 1
13 26430212 Rabaptin5 is recruited to endosomes by Rab4 and Rabex5 to regulate endosome maturation. 2015 Nov 15 4
14 24520163 Diversity and plasticity in Rab GTPase nucleotide release mechanism has consequences for Rab activation and inactivation. 2014 Feb 11 1
15 23382462 RabGEFs are a major determinant for specific Rab membrane targeting. 2013 Feb 4 1
16 21586568 Characterization of RIN3 as a guanine nucleotide exchange factor for the Rab5 subfamily GTPase Rab31. 2011 Jul 8 1
17 20169068 Delayed onset of positive feedback activation of Rab5 by Rabex-5 and Rabaptin-5 in endocytosis. 2010 Feb 16 3
18 19372461 Rab GTPase regulation of VEGFR2 trafficking and signaling in endothelial cells. 2009 Jul 1
19 19819222 Insight into the molecular switch mechanism of human Rab5a from molecular dynamics simulations. 2009 Dec 18 1
20 18425118 A pathway for phagosome maturation during engulfment of apoptotic cells. 2008 May 2
21 18957427 Syndecan-1 ectodomain shedding is regulated by the small GTPase Rab5. 2008 Dec 19 2
22 17395284 Rab-regulated interaction of early endosomes with lipid droplets. 2007 Jun 2
23 17473071 Thyrotropin activates guanosine 5'-diphosphate/guanosine 5'-triphosphate exchange on the rate-limiting endocytic catalyst, Rab5a, in human thyrocytes in vivo and in vitro. 2007 Jul 1
24 17987124 The redox sensor TXNL1 plays a regulatory role in fluid phase endocytosis. 2007 Nov 7 2
25 16410077 Rab5-activating protein 6, a novel endosomal protein with a role in endocytosis. 2006 Feb 17 1
26 16473603 Capture of the small GTPase Rab5 by GDI: regulation by p38 MAP kinase. 2005 2
27 12972505 RIN3: a novel Rab5 GEF interacting with amphiphysin II involved in the early endocytic pathway. 2003 Oct 15 1
28 14600265 Visualization of Rab5 activity in living cells by FRET microscopy and influence of plasma-membrane-targeted Rab5 on clathrin-dependent endocytosis. 2003 Dec 1 1
29 11733506 A novel binding protein composed of homophilic tetramer exhibits unique properties for the small GTPase Rab5. 2002 Feb 1 1
30 12432064 SARA, a FYVE domain protein, affects Rab5-mediated endocytosis. 2002 Dec 15 1
31 11239470 The stress-induced MAP kinase p38 regulates endocytic trafficking via the GDI:Rab5 complex. 2001 Feb 1
32 11703925 Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1. 2001 Jul 1
33 10432006 Differential expression of RAB5A in human lung adenocarcinoma cells with different metastasis potential. 1999 May 1
34 9524116 Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion. 1998 Apr 1 1
35 9323142 A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function. 1997 Sep 19 2
36 8576119 Influence of Mg2+ on the structure and function of Rab5. 1996 Jan 19 2
37 8702787 Kinetics of interaction of Rab5 and Rab7 with nucleotides and magnesium ions. 1996 Aug 23 1
38 8769123 Actions and expression of RAB-GDP dissociation inhibitor in dispersed chief cells from guinea pig stomach. 1996 Aug 5 4
39 7592625 Effect of guanine nucleotide binding on the intrinsic tryptophan fluorescence properties of Rab5. 1995 Oct 13 1
40 7592935 GDP dissociation inhibitor serves as a cytosolic acceptor for newly synthesized and prenylated Rab5. 1995 Nov 10 1
41 7890612 Biochemical and functional characterization of a recombinant GTPase, Rab5, and two of its mutants. 1995 Mar 10 3
42 8137813 Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis. 1994 Mar 15 1
43 8139660 Membrane association of Rab5 mediated by GDP-dissociation inhibitor and accompanied by GDP/GTP exchange. 1994 Mar 10 5
44 8226909 Prenylation of Rab5 is dependent on guanine nucleotide binding. 1993 Nov 15 2
45 8226999 Structure-function relationship of the small GTPase rab5. 1993 Nov 15 1