Title : Recognition and stabilization of geranylgeranylated human Rab5 by the GDP Dissociation Inhibitor (GDI).

Pub. Date : 2019 May

PMID : 29065764






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The GDP dissociation inhibitor (GDI) recognizes membrane-associated Rab5(GDP) and serves to release it into the cytoplasm where it is kept in a soluble state. Guanosine Diphosphate RAB5A, member RAS oncogene family Homo sapiens
2 A detailed new structural and dynamic model for human Rab5(GDP) recognition and binding with human GDI at the early endosome membrane and in its dissociated state is presented. Guanosine Diphosphate RAB5A, member RAS oncogene family Homo sapiens
3 In solution, two different binding modes of the isoprenoid chains inserted into the hydrophobic pocket of the Rab5(GDP):GDI complex can be identified. Guanosine Diphosphate RAB5A, member RAS oncogene family Homo sapiens