Title : RabGEFs are a major determinant for specific Rab membrane targeting.

Pub. Date : 2013 Feb 4

PMID : 23382462






1 Functional Relationships(s)
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1 Here, we demonstrate that Rab-activating guanosine diphosphate/guanosine triphosphate exchange factors (GEFs) display the minimal targeting machinery for recruiting Rabs from the cytosol to the correct membrane using the Rab-GEF pairs Rab5A-Rabex-5, Rab1A-DrrA, and Rab8-Rabin8 as model systems. Guanosine Diphosphate RAB5A, member RAS oncogene family Homo sapiens