Title : Delayed onset of positive feedback activation of Rab5 by Rabex-5 and Rabaptin-5 in endocytosis.

Pub. Date : 2010 Feb 16

PMID : 20169068






3 Functional Relationships(s)
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1 These studies show that the indirect pathway constitutes a positive feedback loop for converting Rab5-GDP to Rab5-GTP on the endosomal membrane and allows sensitive regulation of endosome fusion activity by the levels of Rab5 and Rabex-5 in the cell. Guanosine Diphosphate RAB5A, member RAS oncogene family Homo sapiens
2 These studies show that the indirect pathway constitutes a positive feedback loop for converting Rab5-GDP to Rab5-GTP on the endosomal membrane and allows sensitive regulation of endosome fusion activity by the levels of Rab5 and Rabex-5 in the cell. Guanosine Diphosphate RAB5A, member RAS oncogene family Homo sapiens
3 These studies show that the indirect pathway constitutes a positive feedback loop for converting Rab5-GDP to Rab5-GTP on the endosomal membrane and allows sensitive regulation of endosome fusion activity by the levels of Rab5 and Rabex-5 in the cell. Guanosine Diphosphate RAB5A, member RAS oncogene family Homo sapiens