Title : Visualization of Rab5 activity in living cells by FRET microscopy and influence of plasma-membrane-targeted Rab5 on clathrin-dependent endocytosis.

Pub. Date : 2003 Dec 1

PMID : 14600265






1 Functional Relationships(s)
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1 Although the plasma membrane-localized activity of Rab5 was not detected by light microscopy, overexpression of a GDP-bound mutant of CFP-Rab5(S34N) inhibited internalization of the epidermal growth factor receptor by retaining receptors in clathrin-coated pits. Guanosine Diphosphate RAB5A, member RAS oncogene family Homo sapiens