Disulfiram

aldehyde dehydrogenase 3 family, member A1 ; Rattus norvegicus







52 Article(s)
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1 31426424 Inactivation of Aldehyde Dehydrogenase by Disulfiram in the Presence and Absence of Lipoic Acid or Dihydrolipoic Acid: An in Vitro Study. 2019 Aug 16 2
2 31513972 ALDH1A3 Regulations of Matricellular Proteins Promote Vascular Smooth Muscle Cell Proliferation. 2019 Sep 27 1
3 31885774 Can Lipoic Acid Attenuate Cardiovascular Disturbances Induced by Ethanol and Disulfiram Administration Separately or Jointly in Rats? 2019 1
4 28017615 Pharmacological activation of aldehyde dehydrogenase 2 promotes osteoblast differentiation via bone morphogenetic protein-2 and induces bone anabolic effect. 2017 Feb 1 1
5 27574509 Alcohol and Aldehyde Dehydrogenases Contribute to Sex-Related Differences in Clearance of Zolpidem in Rats. 2016 1
6 22170038 Modulation of aldehyde dehydrogenase activity affects (±)-4-hydroxy-2E-nonenal (HNE) toxicity and HNE-protein adduct levels in PC12 cells. 2012 Jul 1
7 20736996 Disulfiram attenuates drug-primed reinstatement of cocaine seeking via inhibition of dopamine β-hydroxylase. 2010 Nov 5
8 15069620 Acetaldehyde accumulation suppresses Kupffer cell release of TNF-Alpha and modifies acute hepatic inflammation in rats. 2004 2
9 12107032 Microbes and mucosa in the regulation of intracolonic acetaldehyde concentration during ethanol challenge. 2002 Jul-Aug 1
10 11239496 Determination of in vivo adducts of disulfiram with mitochondrial aldehyde dehydrogenase. 2001 Mar 1 1
11 11306033 Overview--in vitro inhibition of aldehyde dehydrogenase by disulfiram and metabolites. 2001 Jan 30 1
12 11306034 In vivo inhibition of aldehyde dehydrogenase by disulfiram. 2001 Jan 30 1
13 10974203 Role of disulfiram in the in vitro inhibition of rat liver mitochondrial aldehyde dehydrogenase. 2000 Oct 1 4
14 10418820 Acetaldehyde prevents nuclear factor-kappa B activation and hepatic inflammation in ethanol-fed rats. 1999 Jul 2
15 10514271 Diethylcarbamoylating/nitroxylating agents as dual action inhibitors of aldehyde dehydrogenase: a disulfiram-cyanamide merger. 1999 Oct 7 1
16 8605194 Possible role of liver cytosolic and mitochondrial aldehyde dehydrogenases in acetaldehyde metabolism. 1996 Apr 9 1
17 8727261 S-methyl-N,N-diethylthiocarbamate sulfoxide and S-methyl-N,N-diethylthiocarbamate sulfone, two candidates for the active metabolite of disulfiram. 1996 May 5
18 12893455 Acetaldehyde metabolism by liver mitochondrial ALDH from UChA and UChB rats: effect of inhibitors. 1996 1
19 7646059 Enzymatic activities of rat liver cytosol 10-formyltetrahydrofolate dehydrogenase. 1995 Aug 20 1
20 7887984 S-methyl N,N-diethylthiocarbamate sulfone, a potential metabolite of disulfiram and potent inhibitor of low Km mitochondrial aldehyde dehydrogenase. 1995 Mar 1 3
21 8519435 Effects of benzodiazepines on aldehyde dehydrogenase activity. 1995 Sep-Oct 3
22 7857714 Aldehyde dehydrogenase involvement in a variant of the brown Norway rat acute myelocytic leukaemia (BNML) that acquired cyclophosphamide resistance in vivo. 1994 1
23 7981417 Identification of novel glutathione conjugates of disulfiram and diethyldithiocarbamate in rat bile by liquid chromatography-tandem mass spectrometry. Evidence for metabolic activation of disulfiram in vivo. 1994 Jul-Aug 4
24 8023334 Investigations on the ethanol-induced flushing reaction: effects of propranolol and dipyridamole on acetaldehyde and prostacyclin metabolism. 1994 May 31 2
25 8048736 In vivo pharmacodynamic studies of the disulfiram metabolite S-methyl N,N-diethylthiolcarbamate sulfoxide: inhibition of liver aldehyde dehydrogenase. 1994 Apr 3
26 8274162 Bioactivation of S-methyl N,N-diethylthiolcarbamate to S-methyl N,N-diethylthiolcarbamate sulfoxide. Implications for the role of cytochrome P450. 1993 Dec 14 1
27 1311578 In vitro and in vivo inhibition of rat liver aldehyde dehydrogenase by S-methyl N,N-diethylthiolcarbamate sulfoxide, a new metabolite of disulfiram. 1992 Feb 4 1
28 1518119 [Effect of cefclidin and E1077, new cephalosporins, on the alcohol-metabolizing system in rats]. 1992 Apr 1
29 1656985 Disulfiram metabolism as a requirement for the inhibition of rat liver mitochondrial low Km aldehyde dehydrogenase. 1991 Sep 12 9
30 2537080 Comparative aspects of disulfiram and its metabolites in the disulfiram-ethanol reaction in the rat. 1989 Feb 1 2
31 2539814 Diethylthiocarbamic acid methyl ester. A potent inhibitor of aldehyde dehydrogenase found in rats treated with disulfiram or diethyldithiocarbamic acid methyl ester. 1989 Apr 1 1
32 2588336 [Kinetics of inhibition of aldehyde dehydrogenase isoenzymes of rat liver by fluorine-containing disulfides]. 1989 Jul-Aug 1
33 2764709 Changes in the inducibility of a hepatic aldehyde dehydrogenase by various effectors. 1989 6
34 2806369 Pharmacological effects of diethylthiocarbamic acid methyl ester, the active metabolite of disulfiram? 1989 Aug 3 1
35 3178876 The metabolism of acetaldehyde and not acetaldehyde itself is responsible for in vivo ethanol-induced lipid peroxidation in rats. 1988 Oct 1 2
36 3342079 Acute effects of the aldehyde dehydrogenase inhibitors, disulfiram, pargyline and cyanamide, on circulating ketone body levels in the rat. 1988 Jan 15 4
37 2438009 Effects of aldehyde dehydrogenase inhibitors on hexobarbital sensitivity and neuroamine metabolism in rat brain. 1987 Apr 21 3
38 3437591 Pharmacokinetics of latamoxef and N-methyltetrazolethiol in rats associated with the development of disulfiram-like effects. 1987 Oct 1
39 2943133 The mechanism of alcohol intolerance produced by various therapeutic agents. 1986 May 1
40 3008991 Identification of hepatocarcinogenesis-associated aldehyde dehydrogenase in normal rat urinary bladder. 1986 May 2
41 3515991 Disulfiram-ethanol reaction in the rat. 1. Blood alcohol, acetaldehyde, and liver aldehyde dehydrogenase relationships. 1986 Jan-Feb 1
42 3820856 A comparative study on the effects of disulfiram and beta-lactam antibiotics on the acetaldehyde-metabolizing system in rats. 1986 Nov 4
43 3994763 Effects of disulfiram on the oxidation of benzaldehyde and acetaldehyde in rat liver. 1985 May 1 2
44 4015841 Ethanol feeding can produce secondary alterations in aldehyde dehydrogenase isozymes. 1985 Jan-Feb 1
45 6346125 The gender of alcohol and aldehyde dehydrogenases. 1983 Mar-Apr 1
46 6346129 Properties and regional distribution of ocular aldehyde dehydrogenase in the rat. 1983 Mar-Apr 1
47 6870943 Studies in vitro on the inactivation of mitochondrial rat-liver aldehyde dehydrogenase by the alcohol-sensitizing compounds cyanamide, 1-aminocyclopropanol and disulfiram. 1983 Jul 15 2
48 7136724 Effects of dopamine-beta-hydroxylase inhibitors FLA-57 and FLA-63 on ethanol metabolism and aldehyde dehydrogenase activity in rats. 1982 Sep 1
49 7159468 Effects of aldehyde dehydrogenase inhibitors on enzymes involved in the metabolism of biogenic aldehydes in rat liver and brain. 1982 Dec 1 1
50 525358 Blood pressure response to ethanol in relation to acetaldehyde levels and dopamine-beta-hydroxylase activity in rats pretreated with disulfiram, cyanamide and coprine. 1979 Oct 1