Pub. Date : 2010 Nov
PMID : 20736996
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The antialcoholism medication disulfiram (Antabuse) inhibits aldehyde dehydrogenase (ALDH), which results in the accumulation of acetaldehyde upon ethanol ingestion and produces the aversive "Antabuse reaction" that deters alcohol consumption. | Disulfiram | aldehyde dehydrogenase 3 family, member A1 | Rattus norvegicus |
| 2 | The antialcoholism medication disulfiram (Antabuse) inhibits aldehyde dehydrogenase (ALDH), which results in the accumulation of acetaldehyde upon ethanol ingestion and produces the aversive "Antabuse reaction" that deters alcohol consumption. | Disulfiram | aldehyde dehydrogenase 3 family, member A1 | Rattus norvegicus |
| 3 | The antialcoholism medication disulfiram (Antabuse) inhibits aldehyde dehydrogenase (ALDH), which results in the accumulation of acetaldehyde upon ethanol ingestion and produces the aversive "Antabuse reaction" that deters alcohol consumption. | Disulfiram | aldehyde dehydrogenase 3 family, member A1 | Rattus norvegicus |
| 4 | The antialcoholism medication disulfiram (Antabuse) inhibits aldehyde dehydrogenase (ALDH), which results in the accumulation of acetaldehyde upon ethanol ingestion and produces the aversive "Antabuse reaction" that deters alcohol consumption. | Disulfiram | aldehyde dehydrogenase 3 family, member A1 | Rattus norvegicus |
| 5 | Disulfiram has also been shown to deter cocaine use, even in the absence of an interaction with alcohol, indicating the existence of an ALDH-independent therapeutic mechanism. | Disulfiram | aldehyde dehydrogenase 3 family, member A1 | Rattus norvegicus |