Title : Pharmacokinetics of latamoxef and N-methyltetrazolethiol in rats associated with the development of disulfiram-like effects.

Pub. Date : 1987 Oct

PMID : 3437591






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Intravenous and subcutaneous administrations of these antibiotics caused a decrease in the low Km aldehyde dehydrogenase (ALDH) activity in liver mitochondria and an increase in blood acetaldehyde level during ethanol metabolism, as in the case of disulfiram. Disulfiram aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus