Tyrosine

interleukin 6 ; Homo sapiens







169 Article(s)
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1 34536415 Early-onset pulmonary and cutaneous vasculitis driven by constitutively active SRC-family kinase HCK. 2022 Apr 1
2 34687791 Induction of IL-6Rα by ATF3 enhances IL-6 mediated sorafenib and regorafenib resistance in hepatocellular carcinoma. 2022 Jan 1 1
3 33382511 STAT3 and its targeting inhibitors in osteosarcoma. 2021 Feb 1
4 34290255 Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer. 2021 Jul 21 1
5 34390807 The anti-parallel dimer binding interface in STAT3 transcription factor is required for the inactivation of cytokine-mediated signal transduction. 2021 Nov 1
6 34703823 STAT3 as a Potential Target for Tumor Suppressive Effects of 15-Deoxy-Δ12,14-prostaglandin J2 in Triple Negative Breast Cancer. 2021 Sep 30 1
7 31068940 CD28 Individual Signaling Up-regulates Human IL-17A Expression by Promoting the Recruitment of RelA/NF-κB and STAT3 Transcription Factors on the Proximal Promoter. 2019 1
8 31080186 Fraxetin Suppresses Proliferation of Non-Small-Cell Lung Cancer Cells via Preventing Activation of Signal Transducer and Activator of Transcription 3. 2019 May 1
9 28558479 Mechanisms of Mitochondrial Redox Signaling in Psychosocial Stress-Responsive Systems: New Insights into an Old Story. 2018 Mar 20 1
10 29456111 Methyllucidone inhibits STAT3 activity by regulating the expression of the protein tyrosine phosphatase MEG2 in DU145 prostate carcinoma cells. 2018 Mar 1 2
11 29581268 IRF9 and unphosphorylated STAT2 cooperate with NF-κB to drive IL6 expression. 2018 Apr 10 2
12 29660364 Silibinin is a direct inhibitor of STAT3. 2018 Jun 1
13 29807795 Piperlongumine derivative, CG-06, inhibits STAT3 activity by direct binding to STAT3 and regulating the reactive oxygen species in DU145 prostate carcinoma cells. 2018 Aug 1 1
14 28208810 Shp2 Plays a Critical Role in IL-6-Induced EMT in Breast Cancer Cells. 2017 Feb 13 1
15 28722170 Activation of the B-cell receptor successively activates NF-κB and STAT3 in chronic lymphocytic leukemia cells. 2017 Nov 15 3
16 26423306 Serum Phenylalanine, Tyrosine, and their Ratio in Acute Ischemic Stroke: on the Trail of a Biomarker? 2016 Jan 1
17 26893580 Interleukin-6 is a potential therapeutic target in interleukin-6 dependent, estrogen receptor-α-positive breast cancer. 2016 1
18 27048653 A New STAT3-binding Partner, ARL3, Enhances the Phosphorylation and Nuclear Accumulation of STAT3. 2016 May 20 1
19 27502766 Mitochondrial STAT3 is negatively regulated by SOCS3 and upregulated after spinal cord injury. 2016 Oct 1
20 26166037 Homoharringtonine induces apoptosis and inhibits STAT3 via IL-6/JAK1/STAT3 signal pathway in Gefitinib-resistant lung cancer cells. 2015 Jul 13 1
21 26384335 Effects of Reducing Suppressors of Cytokine Signaling-3 (SOCS3) Expression on Dendritic Outgrowth and Demyelination after Spinal Cord Injury. 2015 2
22 26572585 Role of Integrin β4 in Lung Endothelial Cell Inflammatory Responses to Mechanical Stress. 2015 Nov 17 1
23 23032719 Evodiamine inhibits STAT3 signaling by inducing phosphatase shatterproof 1 in hepatocellular carcinoma cells. 2013 Jan 28 6
24 23166300 TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers. 2013 Feb 2
25 23303450 The IL-6 trans-signaling-STAT3 pathway mediates ECM and cellular proliferation in fibroblasts from hypertrophic scar. 2013 May 1
26 23583378 Metastasis suppressor Nm23-H1 inhibits STAT3 signaling via a negative feedback mechanism. 2013 May 10 1
27 23906537 The Fer tyrosine kinase acts as a downstream interleukin-6 effector of androgen receptor activation in prostate cancer. 2013 Dec 5 1
28 24082147 STAT3 activation in response to IL-6 is prolonged by the binding of IL-6 receptor to EGF receptor. 2013 Oct 15 1
29 24152848 Novel path to IL-6 trans-signaling through thrombin-induced soluble IL-6 receptor release by platelets. 2013 Jul-Sep 2
30 24192293 Dominant-negative activity of the STAT3-Y705F mutant depends on the N-terminal domain. 2013 Nov 5 1
31 21954831 Interleukin-6 autocrine signaling mediates melatonin MT(1/2) receptor-induced STAT3 Tyr(705) phosphorylation. 2012 May 2
32 22197944 STAT3 genotypic variation and cellular STAT3 activation and colon leukocyte recruitment in pediatric Crohn disease. 2012 Jul 1
33 22280969 Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3). 2012 Jan 26 1
34 23125416 CCR1-mediated STAT3 tyrosine phosphorylation and CXCL8 expression in THP-1 macrophage-like cells involve pertussis toxin-insensitive Gα(14/16) signaling and IL-6 release. 2012 Dec 1 1
35 20978825 Adiponectin reduces C-reactive protein expression and downregulates STAT3 phosphorylation induced by IL-6 in HepG2 cells. 2011 Jan 1
36 21216930 JAK1 activates STAT3 activity in non-small-cell lung cancer cells and IL-6 neutralizing antibodies can suppress JAK1-STAT3 signaling. 2011 Mar 1
37 21625522 Dynamics of the STAT3 transcription factor: nuclear import dependent on Ran and importin-β1. 2011 1
38 21625597 Two naturally occurring terpenes, dehydrocostuslactone and costunolide, decrease intracellular GSH content and inhibit STAT3 activation. 2011 1
39 21690253 Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas. 2011 Jul 4 1
40 20233902 Sulforaphane inhibits constitutive and interleukin-6-induced activation of signal transducer and activator of transcription 3 in prostate cancer cells. 2010 Apr 2
41 20379953 Kansuinine A and Kansuinine B from Euphorbia kansui L. inhibit IL-6-induced Stat3 activation. 2010 Oct 1
42 20383201 Dasatinib inhibits site-specific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases. 2010 Jun 3 3
43 20693312 Glucocorticoids potentiate IL-6-induced SP-B expression in H441 cells by enhancing the JAK-STAT signaling pathway. 2010 Oct 1
44 20724373 Withaferin A inhibits activation of signal transducer and activator of transcription 3 in human breast cancer cells. 2010 Nov 2
45 20728433 Identification of BCAP-(L) as a negative regulator of the TLR signaling-induced production of IL-6 and IL-10 in macrophages by tyrosine phosphoproteomics. 2010 Sep 17 1
46 20851386 Neutralization of interleukin (IL)-10 released by monocytes/macrophages enhances the up-regulatory effect of monocyte/macrophage-derived IL-6 on expressions of IL-6 and MUC1, and migration in HT-29 colon cancer cells. 2010 1
47 20876575 Suppressor of cytokine signaling 3 inhibits LPS-induced IL-6 expression in osteoblasts by suppressing CCAAT/enhancer-binding protein {beta} activity. 2010 Nov 26 1
48 18988672 S-glutathionylation impairs signal transducer and activator of transcription 3 activation and signaling. 2009 Mar 1
49 19009233 The fungal secondary metabolite trichodimerol inhibits TGF-β dependent cellular effects and tube formation of MDA-MB-231 cells. 2009 Dec 1
50 19182994 Ha-ras oncogene-induced Stat3 phosphorylation enhances oncogenicity of the cell. 2009 Mar 2