Title : Suppressor of cytokine signaling 3 inhibits LPS-induced IL-6 expression in osteoblasts by suppressing CCAAT/enhancer-binding protein {beta} activity.

Pub. Date : 2010 Nov 26

PMID : 20876575






1 Functional Relationships(s)
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1 We found that tyrosine 204 of the SOCS box, the SH2 domain, and the N-terminal kinase inhibitory region (KIR) of SOCS3 were all involved in its IL-6 inhibition. Tyrosine interleukin 6 Homo sapiens