Title : Piperlongumine derivative, CG-06, inhibits STAT3 activity by direct binding to STAT3 and regulating the reactive oxygen species in DU145 prostate carcinoma cells.

Pub. Date : 2018 Aug 1

PMID : 29807795






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 CG-06 inhibited STAT3 phosphorylation at tyrosine 705 in a dose- and time dependent manner in DU-145 cells and suppressed IL-6-induced STAT3 phosphorylation at Tyr-705 in DU-145 and LNCaP cell lines. Tyrosine interleukin 6 Homo sapiens