Title : TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers.

Pub. Date : 2013 Feb

PMID : 23166300






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Tyrosine phosphorylation-dependent signaling, as mediated by members of the epidermal growth factor receptor (EGFR) family (ErbB1 to -4) of protein tyrosine kinases (PTKs), Src family PTKs (SFKs), and cytokines such as interleukin-6 (IL-6) that signal via signal transducer and activator of transcription 3 (STAT3), is critical to the development and progression of many human breast cancers. Tyrosine interleukin 6 Homo sapiens
2 Tyrosine phosphorylation-dependent signaling, as mediated by members of the epidermal growth factor receptor (EGFR) family (ErbB1 to -4) of protein tyrosine kinases (PTKs), Src family PTKs (SFKs), and cytokines such as interleukin-6 (IL-6) that signal via signal transducer and activator of transcription 3 (STAT3), is critical to the development and progression of many human breast cancers. Tyrosine interleukin 6 Homo sapiens