Guanosine Diphosphate

eukaryotic translation elongation factor 1 alpha 1 ; Homo sapiens







58 Article(s)
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1 31058500 Elongation Factor Tu's Nucleotide Binding Is Governed by a Thermodynamic Landscape Unique among Bacterial Translation Factors. 2019 Jul 3 4
2 29417736 mRNA-Independent way to regulate translation elongation rate in eukaryotic cells. 2018 Mar 4
3 27837019 Two proofreading steps amplify the accuracy of genetic code translation. 2016 Nov 29 4
4 26073967 Structural outline of the detailed mechanism for elongation factor Ts-mediated guanine nucleotide exchange on elongation factor Tu. 2015 Jul 1
5 25326326 Mammalian translation elongation factor eEF1A2: X-ray structure and new features of GDP/GTP exchange mechanism in higher eukaryotes. 2014 Nov 10 6
6 24079513 A kinetic safety gate controlling the delivery of unnatural amino acids to the ribosome. 2013 Nov 13 1
7 22378069 Raf kinases mediate the phosphorylation of eukaryotic translation elongation factor 1A and regulate its stability in eukaryotic cells. 2012 Mar 1 1
8 22740700 Thermodynamics of the GTP-GDP-operated conformational switch of selenocysteine-specific translation factor SelB. 2012 Aug 10 2
9 20838377 Guanine nucleotides regulate sphingosine kinase 1 activation by eukaryotic elongation factor 1A and provide a mechanism for eEF1A-associated oncogenesis. 2011 Jan 20 6
10 21665947 Mitotic modulation of translation elongation factor 1 leads to hindered tRNA delivery to ribosomes. 2011 Aug 12 1
11 18562321 Guanine nucleotide exchange factor independence of the G-protein eEF1A through novel mutant forms and biochemical properties. 2008 Aug 22 1
12 18773979 Mechanism of the chemical step for the guanosine triphosphate (GTP) hydrolysis catalyzed by elongation factor Tu. 2008 Dec 3
13 17397188 Mechanism of EF-Ts-catalyzed guanine nucleotide exchange in EF-Tu: contribution of interactions mediated by helix B of EF-Tu. 2007 May 1 1
14 17704259 Structural insights into the interaction of the evolutionarily conserved ZPR1 domain tandem with eukaryotic EF1A, receptors, and SMN complexes. 2007 Aug 28 1
15 16675455 Mg2+ and a key lysine modulate exchange activity of eukaryotic translation elongation factor 1B alpha. 2006 Jul 14 1
16 16717093 The importance of P-loop and domain movements in EF-Tu for guanine nucleotide exchange. 2006 Jul 28 1
17 16876786 Elongation factor Tu-targeted antibiotics: four different structures, two mechanisms of action. 2006 Aug 21 2
18 17042495 Delayed release of inorganic phosphate from elongation factor Tu following GTP hydrolysis on the ribosome. 2006 Oct 24 2
19 15317456 Structural basis for the binding of didemnins to human elongation factor eEF1A and rationale for the potent antitumor activity of these marine natural products. 2004 Aug 26 1
20 15581367 Effects of the antibiotic pulvomycin on the elongation factor Tu-dependent reactions. Comparison with other antibiotics. 2004 Dec 14 4
21 14623968 Translationally controlled tumor protein acts as a guanine nucleotide dissociation inhibitor on the translation elongation factor eEF1A. 2003 Nov 25 1
22 12354112 Novel complexes of mammalian translation elongation factor eEF1A.GDP with uncharged tRNA and aminoacyl-tRNA synthetase. Implications for tRNA channeling. 2002 Oct 3
23 11373622 Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex. 2001 Jun 9
24 11524957 [Functional compartmentation of the translation apparatus and channeling of tRNA/aminoacyl-tRNA in cells of higher eukaryotes]. 2001 Jul-Aug 1
25 11045624 Interaction of mammalian mitochondrial elongation factor EF-Tu with guanine nucleotides. 2000 Sep 11
26 10376675 Structural information for explaining the molecular mechanism of protein biosynthesis. 1999 Jun 4 1
27 9218959 Macromolecular mimicry in protein biosynthesis. 1997 3
28 9254632 The conformational properties of elongation factor G and the mechanism of translocation. 1997 Aug 19 9
29 8665868 Enacyloxin IIa, an inhibitor of protein biosynthesis that acts on elongation factor Tu and the ribosome. 1996 May 15 2
30 7782317 Phosphorylation of elongation factor Tu prevents ternary complex formation. 1995 Jun 16 3
31 7851417 Interaction studies between elongation factor Tu and anthraniloyl-fluorescent analogues of guanyl nucleotides. 1995 Jan 15 3
32 8722020 tRNA-ribosome interactions. 1995 Nov-Dec 4
33 8462668 How does the switch II region of G-domains work? 1993 Mar 29 1
34 1740128 Effects of ions on the intrinsic activities of c-H-ras protein p21. A comparison with elongation factor Tu. 1992 Feb 15 2
35 1663155 Computer-aided active-site-directed modeling of the herpes simplex virus 1 and human thymidine kinase. 1991 Oct 2
36 2110000 Effects of nucleotide- and aurodox-induced changes in elongation factor Tu conformation upon its interactions with aminoacyl transfer RNA. A fluorescence study. 1990 Feb 20 14
37 2119812 Mutagenesis of the NH2-terminal domain of elongation factor Tu. 1990 Aug 27 1
38 2508560 Site-directed mutagenesis of the GDP binding domain of bacterial elongation factor Tu. 1989 Nov 1 2
39 2510820 Conformation and reactivity changes induced by N-methylkirromycin (aurodox) in elongation factor Tu. 1989 Aug 22 1
40 3181143 Structure-function relationships in the GTP binding domain of EF-Tu: mutation of Val20, the residue homologous to position 12 in p21. 1988 Sep 3
41 3276311 Proton NMR studies of the GDP.Mg2+ complex of the Ha-ras oncogene product p21. 1988 Jan 15 3
42 3350808 The kinetic mechanism of the release of nucleotide from elongation factor Tu promoted by elongation factor Ts determined by pressure relaxation studies. 1988 Apr 5 2
43 3297141 Effects of the mutation glycine-222----aspartic acid on the functions of elongation factor Tu. 1987 Apr 7 1
44 3651421 Intrinsic fluorescence of elongation factor Tu in its complexes with GDP and elongation factor Ts. 1987 Jun 30 4
45 3514605 The reaction of ribosomes with elongation factor Tu.GTP complexes. Aminoacyl-tRNA-independent reactions in the elongation cycle determine the accuracy of protein synthesis. 1986 Apr 15 2
46 6323160 Specific alterations of the EF-Tu polypeptide chain considered in the light of its three-dimensional structure. 1984 Jan 2
47 6377304 Cross-linking of tRNA at two different sites of the elongation factor Tu. 1984 Jul 1
48 6765192 The elongation factor Tu.kirromycin complex has two binding sites for tRNA molecules. 1982 4
49 6953412 Mechanism of polypeptide chain initiation in eukaryotes and its control by phosphorylation of the alpha subunit of initiation factor 2. 1982 Apr 12
50 16453409 Catalytic effects of elongation factor Ts on polypeptide synthesis. 1982 2