Title : Structural outline of the detailed mechanism for elongation factor Ts-mediated guanine nucleotide exchange on elongation factor Tu.

Pub. Date : 2015 Jul

PMID : 26073967






1 Functional Relationships(s)
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1 We have determined the crystal structures of the following reaction intermediates: two structures of EF-Tu:GDP:EF-Ts (2.2 and 1.8A resolution), EF-Tu:PO4:EF-Ts (1.9A resolution), EF-Tu:GDPNP:EF-Ts (2.2A resolution) and EF-Tu:GDPNP:pulvomycin:Mg(2+):EF-Ts (3.5A resolution). Guanosine Diphosphate eukaryotic translation elongation factor 1 alpha 1 Homo sapiens