Title : Conformation and reactivity changes induced by N-methylkirromycin (aurodox) in elongation factor Tu.

Pub. Date : 1989 Aug 22

PMID : 2510820






1 Functional Relationships(s)
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1 These results strongly support the hypothesis that aurodox not only confers a "GTP-like" conformation to the EF-Tu.GDP complex but also produces a less stable folding of the protein around the tryptophan residue that may contribute to the multiple functional effects of this antibiotic. Guanosine Diphosphate eukaryotic translation elongation factor 1 alpha 1 Homo sapiens