Title : Structural basis for the binding of didemnins to human elongation factor eEF1A and rationale for the potent antitumor activity of these marine natural products.

Pub. Date : 2004 Aug 26

PMID : 15317456






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 In the GDP-bound form of eEF1A, this binding site exists only as two separate halves, which accounts for the much greater affinity of didemnins for the GTP-bound form of this elongation factor. Guanosine Diphosphate eukaryotic translation elongation factor 1 alpha 1 Homo sapiens