pirinixic acid

peroxisome proliferator activated receptor alpha ; Mus musculus







97 Article(s)
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1 34387904 YAP-TEAD mediates PPAR α-induced hepatomegaly and liver regeneration in mice. 2022 Jan 1
2 35007830 Real ambient particulate matter-induced lipid metabolism disorder: Roles of peroxisome proliferators-activated receptor alpha. 2022 Feb 2
3 35526488 PPARα agonist WY-14,643 induces the PLA2/COX-2/ACOX1 pathway to enhance peroxisomal lipid metabolism and ameliorate alcoholic fatty liver in mice. 2022 Jul 12 1
4 33754023 Deficiency of telomere-associated repressor activator protein 1 precipitates cardiac aging in mice via p53/PPARα signaling. 2021 1
5 33835704 High phosphate impairs arterial endothelial function through AMPK-related pathways in mouse resistance arteries. 2021 Apr 1
6 34265279 PPARα agonist WY-14,643 induces adipose atrophy and fails to blunt chronic ethanol-induced hepatic fat accumulation in mice lacking adipose FGFR1. 2021 Oct 1
7 34390780 Activation of PPARα-catalase pathway reverses alcoholic liver injury via upregulating NAD synthesis and accelerating alcohol clearance. 2021 Oct 2
8 32506644 The branched-chain amino acids valine and leucine have differential effects on hepatic lipid metabolism. 2020 Jul 1
9 32534105 Regulation of Hox and ParaHox genes by perfluorochemicals in mouse liver. 2020 Aug 1
10 32791799 [Study of the effect of CHOP signaling molecule in PPARα activation and inhibition with response to inflammation in mice with acute liver failure]. 2020 Jul 20 1
11 32826849 The critical role of PPARα in the binary switch between life and death induced by endoplasmic reticulum stress. 2020 Aug 11 2
12 30504232 Hepatic transcriptome analysis from HFD-fed mice defines a long noncoding RNA regulating cellular cholesterol levels. 2019 Feb 1
13 30729704 Chondroprotection of PPARα activation by WY14643 via autophagy involving Akt and ERK in LPS-treated mouse chondrocytes and osteoarthritis model. 2019 Apr 5
14 30957417 Resveratrol inhibits lipid accumulation in the intestine of atherosclerotic mice and macrophages. 2019 Jun 1
15 29141109 Hepatic peroxisome proliferator-activated receptor alpha mediates the major metabolic effects of Wy-14643. 2018 May 6
16 29659121 Glucagon-like peptide-1 ameliorates cardiac lipotoxicity in diabetic cardiomyopathy via the PPARα pathway. 2018 Aug 1
17 29722018 Hippocampal PPARα is a novel therapeutic target for depression and mediates the antidepressant actions of fluoxetine in mice. 2018 Jul 2
18 28007964 Peroxisome proliferator-activated receptor-α accelerates α-chlorofatty acid catabolism. 2017 Feb 2
19 28017641 WY-14643, a selective agonist of peroxisome proliferator-activated receptor-α, ameliorates lipopolysaccharide-induced depressive-like behaviors by preventing neuroinflammation and oxido-nitrosative stress in mice. 2017 Feb 5
20 28600667 Peroxisome proliferator-activated receptor alpha mediates C/EBP homologous protein to protect mice from acute liver failure. 2017 Sep 1
21 28607105 Acyl-CoA Thioesterase 1 (ACOT1) Regulates PPARα to Couple Fatty Acid Flux With Oxidative Capacity During Fasting. 2017 Aug 2
22 28711683 Anti-obesogenic effects of WY14643 (PPAR-alpha agonist): Hepatic mitochondrial enhancement and suppressed lipogenic pathway in diet-induced obese mice. 2017 Sep 1
23 27422264 WY14643 Attenuates the Scopolamine-Induced Memory Impairments in Mice. 2016 Nov 4
24 27482818 Peroxisome proliferator-activated receptor alpha acts as a mediator of endoplasmic reticulum stress-induced hepatocyte apoptosis in acute liver failure. 2016 Jul 1 1
25 25388293 WY14643 produces anti-depressant-like effects in mice via the BDNF signaling pathway. 2015 May 1
26 25695641 Regulation of IGFBP-2 expression during fasting. 2015 May 1 3
27 25703193 Cytochrome P450 1B1: An unexpected modulator of liver fatty acid homeostasis. 2015 Apr 1 1
28 25896250 Inhibition of Dexamethasone-induced Fatty Liver Development by Reducing miR-17-5p Levels. 2015 Jul 1
29 25913736 Medium-chain dicarboxylic acylcarnitines as markers of n-3 PUFA-induced peroxisomal oxidation of fatty acids. 2015 Aug 1
30 26125906 WY14643 combined with all-trans retinoic acid acts via p38 MAPK to induce "browning" of white adipocytes in mice. 2015 Jun 26 1
31 24876382 Hypoxia-inducible lipid droplet-associated (HILPDA) is a novel peroxisome proliferator-activated receptor (PPAR) target involved in hepatic triglyceride secretion. 2014 Jul 11 1
32 25511156 Transcriptomic signatures of peroxisome proliferator-activated receptor α (PPARα) in different mouse liver models identify novel aspects of its biology. 2014 Dec 15 3
33 25511408 [The protective role of peroxisome proliferator activated receptors-α and pathomechanism in D-galactosamine/lipopolysaccharide- induced acute liver failure in rats]. 2014 Sep 1
34 23362873 In vivo imaging reveals selective PPAR activity in the skin of peroxisome proliferator-activated receptor responsive element-luciferase reporter mice. 2013 Feb 3
35 23388073 Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol mediated liver fibrosis in mice. 2013 Feb 6 1
36 23685729 Effects of PPAR-α agonist and IGF-1 on estrogen sulfotransferase in human vascular endothelial and smooth muscle cells. 2013 Jul 1
37 23724059 PPAR-alpha agonists as novel antiepileptic drugs: preclinical findings. 2013 1
38 23727576 Activation of PPARα by Wy-14643 ameliorates systemic lipopolysaccharide-induced acute lung injury. 2013 Jul 5 3
39 22160327 The adaptor-related protein complex 2, alpha 2 subunit (AP2α2) gene is a peroxisome proliferator-activated receptor cardiac target gene. 2012 Jan 1
40 22274564 Detailed transcriptomics analysis of the effect of dietary fatty acids on gene expression in the heart. 2012 Mar 19 1
41 22607296 Co-treatment with retinyl retinoate and a PPARα agonist reduces retinoid dermatitis. 2012 Jun 1
42 22966226 Peroxisome Proliferator-Activated Receptor α Plays an Important Role in the Expression of Monocyte Chemoattractant Protein-1 and Neointimal Hyperplasia after Vascular Injury. 2012 1
43 23008696 PPARα-Independent Arterial Smooth Muscle Relaxant Effects of PPARα Agonists. 2012 3
44 21245137 Peroxisome proliferator-activated receptor (PPAR) gene profiling uncovers insulin-like growth factor-1 as a PPARalpha target gene in cardioprotection. 2011 Apr 22 1
45 21633371 Efficacy of combined peroxisome proliferator-activated receptor-α ligand and glucocorticoid therapy in a murine model of atopic dermatitis. 2011 Sep 1
46 21811494 A Comparative Study of Mouse Hepatic and Intestinal Gene Expression Profiles under PPARα Knockout by Gene Set Enrichment Analysis. 2011 1
47 21846997 Clofibrate relaxes the longitudinal smooth muscle of the mouse distal colon through calcium-mediated desensitisation of contractile machinery. 2011 1
48 21963508 Two thiophenes compounds are partial peroxisome proliferator-activated receptor α/γ dual agonists. 2011 1
49 22208561 Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol induced steatohepatitis in mice. 2011 Dec 30 2
50 19998413 PPAR-beta facilitating maturation of hepatic-like tissue derived from mouse embryonic stem cells accompanied by mitochondriogenesis and membrane potential retention. 2010 Feb 15 1