Title : Activation of PPARĪ±-catalase pathway reverses alcoholic liver injury via upregulating NAD synthesis and accelerating alcohol clearance.

Pub. Date : 2021 Oct

PMID : 34390780






2 Functional Relationships(s)
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1 Mouse studies were conducted to determine the effect of PPARalpha reactivation by Wy14,643 on alcoholic hepatotoxicity and how catalase is involved in mediating such effects. pirinixic acid peroxisome proliferator activated receptor alpha Mus musculus
2 PPARalpha reactivation by Wy14,643 effectively reversed alcohol-induced liver damage in mice. pirinixic acid peroxisome proliferator activated receptor alpha Mus musculus