Title : Peroxisome proliferator-activated receptor (PPAR) gene profiling uncovers insulin-like growth factor-1 as a PPARalpha target gene in cardioprotection.

Pub. Date : 2011 Apr 22

PMID : 21245137






1 Functional Relationships(s)
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1 In line, Wy-14643-mediated PPARalpha activation in the wild-type mouse heart resulted in up-regulation of igf-1 transcript abundance and provided protection against cardiomyocyte apoptosis following ischemia/reperfusion or biomechanical stress. pirinixic acid peroxisome proliferator activated receptor alpha Mus musculus