Doxorubicin

caspase 3 ; Homo sapiens







224 Article(s)
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1 34656704 The diuretic amiloride attenuates doxorubicin-induced chemobrain in rats: Behavioral and mechanistic study. 2022 Jan 1
2 34874743 Identification of Drug Transporter Genomic Variants and Inhibitors That Protect Against Doxorubicin-Induced Cardiotoxicity. 2022 Jan 25 1
3 35057107 Anticancer Activity of Urease Mimetic Cobalt (III) Complexes on A549-Lung Cancer Cells: Targeting the Acidic Microenvironment. 2022 Jan 17 1
4 35113358 Lupeol synergizes with doxorubicin to induce anti-proliferative and apoptotic effects on breast cancer cells. 2022 Jun 1
5 35216449 Employing CRISPR-Cas9 to Generate CD133 Synthetic Lethal Melanoma Stem Cells. 2022 Feb 20 1
6 35327403 Infigratinib (BGJ 398), a Pan-FGFR Inhibitor, Targets P-Glycoprotein and Increases Chemotherapeutic-Induced Mortality of Multidrug-Resistant Tumor Cells. 2022 Mar 3 1
7 35395977 [Effect of Doxycycline on Intrinsic Apoptosis of Myeloma Cell Line H929 and Its Mechanism]. 2022 Apr 3
8 35447298 Caspase-3 mediated switch therapy of self-triggered and long-acting prodrugs for metastatic TNBC. 2022 Jun 2
9 35452763 Feedback amplification of senolysis using caspase-3-cleavable peptide-doxorubicin conjugate and 2DG. 2022 Jun 1
10 35453640 Interleukin-10 Mitigates Doxorubicin-Induced Endoplasmic Reticulum Stress as Well as Cardiomyopathy. 2022 Apr 13 1
11 35503006 Effects of doxorubicin and apigenin on chronic myeloid leukemia cells (K562) in vitro: anti-proliferative and apoptosis induction assessments. 2022 May 3 2
12 35579133 Enzalutamide Overcomes Dihydrotestosterone Induced Chemo-Resistance In Triple-Negative Breast Cancer Cells via Apoptosis. 2022 May 9 1
13 32770328 Study on the Molecular Mechanisms Against Human Breast Cancer from Insight of Elemental Distribution in Tissue Based on Laser-Induced Breakdown Spectroscopy (LIBS). 2021 May 2
14 33390801 USP37 downregulation elevates the Chemical Sensitivity of Human Breast Cancer Cells to Adriamycin. 2021 1
15 33571711 Epithelial Regeneration After Doxorubicin Arises Primarily From Early Progeny of Active Intestinal Stem Cells. 2021 2
16 33589596 Caspase 3/GSDME-dependent pyroptosis contributes to chemotherapy drug-induced nephrotoxicity. 2021 Feb 15 1
17 33639139 Anti-CD19 mAb modified mesoporous titanium dioxide as exclusively targeting vector for efficient B-lymphoblastic leukemia therapy. 2021 Jul 1
18 33850567 Hydroxyl safflower yellow B combined with doxorubicin inhibits the proliferation of human breast cancer MCF-7 cells. 2021 May 1
19 33923922 Mangiferin Inhibits Apoptosis in Doxorubicin-Induced Vascular Endothelial Cells via the Nrf2 Signaling Pathway. 2021 Apr 20 1
20 34126102 Modeling hypoxia facilitates cancer cell survival through downregulation of p53 expression. 2021 Aug 25 1
21 34208283 The Long-Term DEHP Exposure Confers Multidrug Resistance of Triple-Negative Breast Cancer Cells through ABC Transporters and Intracellular ROS. 2021 Jun 11 1
22 34233077 Increased cell-free fetal DNA release after apoptosis and sterile inflammation in human trophoblast cells. 2021 Nov 1
23 34237409 Polymeric micelles of a copolymer composed of all-trans retinoic acid, methoxy-poly(ethylene glycol), and b-poly(N-(2 hydroxypropyl) methacrylamide) as a doxorubicin-delivery platform and for combination chemotherapy in breast cancer. 2021 Sep 5 1
24 34319045 Anti-Proliferative Effect of Doxorubicin-Loaded AS1411 Aptamer on Colorectal Cancer Cell. 2021 Jul 1 2
25 34343539 Novel in vivo potential of trifluoperazine to ameliorate doxorubicin-induced cardiotoxicity involves suppression of NF-κB and apoptosis. 2021 Oct 15 1
26 34353488 A caspase-3 activatable photoacoustic probe for in vivo imaging of tumor apoptosis. 2021 1
27 34369076 Caspase-3-mediated GSDME induced Pyroptosis in breast cancer cells through the ROS/JNK signalling pathway. 2021 Sep 2
28 35095524 A GSH/CB Dual-Controlled Self-Assembled Nanomedicine for High-Efficacy Doxorubicin-Resistant Breast Cancer Therapy. 2021 1
29 31630586 Edaravone and benidipine protect myocardial damage by regulating mitochondrial stress, apoptosis signalling and cardiac biomarkers against doxorubicin-induced cardiotoxicity. 2020 Jul 3 1
30 31707337 Magnoflorine improves sensitivity to doxorubicin (DOX) of breast cancer cells via inducing apoptosis and autophagy through AKT/mTOR and p38 signaling pathways. 2020 Jan 1
31 31833715 Therapeutic Potentials of Inhibition of Jumonji C Domain-containing Demethylases in Acute Myeloid Leukemia 2020 Feb 20 1
32 31843629 Parameritannin A-2 from Urceola huaitingii enhances doxorubicin-induced mitochondria-dependent apoptosis by inhibiting the PI3K/Akt, ERK1/2 and p38 pathways in gastric cancer cells. 2020 Jan 25 1
33 32032743 hsa-miR-766-5p as a new regulator of mitochondrial apoptosis pathway for discriminating of cell death from cardiac differentiation. 2020 Apr 30 1
34 32145585 Kaempferol protects mitochondria and alleviates damages against endotheliotoxicity induced by doxorubicin. 2020 Jun 1
35 32185414 GATA4-targeted compound exhibits cardioprotective actions against doxorubicin-induced toxicity in vitro and in vivo: establishment of a chronic cardiotoxicity model using human iPSC-derived cardiomyocytes. 2020 Jun 1
36 32308718 Chemopreventive Effects and Antioxidant Capacity of Combined Leaf Extracts of Sesamum angustifolium (Oliv.) Engl. and Hibiscus articulatus on Rhabdomyosarcoma. 2020 1
37 32422307 Thymoquinone potentiates miR-16 and miR-375 expressions in hepatocellular carcinoma. 2020 Aug 1 3
38 32592377 Hsp90 Inhibitor; NVP-AUY922 in Combination with Doxorubicin Induces Apoptosis and Downregulates VEGF in MCF-7 Breast Cancer Cell Line. 2020 Jun 1 1
39 32620145 Long non-coding RNA LINC00426 contributes to doxorubicin resistance by sponging miR-4319 in osteosarcoma. 2020 Jul 3 1
40 32647151 Doxorubicin-loaded iron oxide nanoparticles for glioblastoma therapy: a combinational approach for enhanced delivery of nanoparticles. 2020 Jul 9 1
41 32712543 The carotenoid fucoxanthin can sensitize multidrug resistant cancer cells to doxorubicin via induction of apoptosis, inhibition of multidrug resistance proteins and metabolic enzymes. 2020 Oct 1
42 32851890 Investigating the Impact of OGT Inhibition on Doxorubicin- and Docetaxel-Induced Cytotoxicity in PC-3 and WPMY-1 Cells. 2020 Nov/Dec 1
43 32919690 Folic acid-modified bovine serum albumin nanoparticles with doxorubicin and chlorin e6 for effective combinational chemo-photodynamic therapy. 2020 Dec 1
44 33298102 Prophylactic, single-drug cardioprotection in a comparative, experimental study of doxorubicin-induced cardiomyopathy. 2020 Dec 9 1
45 30483812 Levistolide A synergistically enhances doxorubicin‑induced apoptosis of k562/dox cells by decreasing MDR1 expression through the ubiquitin pathway. 2019 Feb 1
46 30609135 Resveratrol potentially increased the tumoricidal effect of doxorubicin on SKOV3 cancer stem cells in vitro. 2019 Jan 4 1
47 30659905 The novel strategy for concurrent chemoradiotherapy by conjugating the apoptotic cell-binding moiety to caspase-3 activated doxorubicin prodrug. 2019 Feb 28 1
48 30988617 Psoralen-loaded lipid-polymer hybrid nanoparticles enhance doxorubicin efficacy in multidrug-resistant HepG2 cells. 2019 1
49 31128433 5-Chlorobenzofuran-2-carboxamides: From allosteric CB1 modulators to potential apoptotic antitumor agents. 2019 Sep 1 1
50 31132617 Liposome-coated nano doxorubicin induces apoptosis on oral squamous cell carcinoma CAL-27 cells. 2019 Jul 2