Doxorubicin

caspase 3 ; Homo sapiens







224 Article(s)
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51 31202781 Oridonin synergistically enhances the anti-tumor efficacy of doxorubicin against aggressive breast cancer via pro-apoptotic and anti-angiogenic effects. 2019 Aug 1
52 31319070 Nicorandil prevents doxorubicin-induced human umbilical vein endothelial cell apoptosis. 2019 Sep 15 2
53 31401980 ACOX1 destabilizes p73 to suppress intrinsic apoptosis pathway and regulates sensitivity to doxorubicin in lymphoma cells. 2019 Sep 1
54 31445005 Doxorubicin induces cardiomyocyte pyroptosis via the TINCR-mediated posttranscriptional stabilization of NLR family pyrin domain containing 3. 2019 Nov 1
55 31563593 Pathophysiological roles of autophagy and aldo-keto reductases in development of doxorubicin resistance in gastrointestinal cancer cells. 2019 Dec 1 1
56 31571866 Tuning the surface coating of IONs toward efficient sonochemical tethering and sustained liberation of topoisomerase II poisons. 2019 1
57 31885804 Tetramethylpyrazine Attenuates the Endotheliotoxicity and the Mitochondrial Dysfunction by Doxorubicin via 14-3-3γ/Bcl-2. 2019 1
58 33405660 Biodegradable Porous Silicon Nanocontainers as an Effective Drug Carrier for Regulation of the Tumor Cell Death Pathways. 2019 Nov 11 1
59 29141199 Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative. 2018 Jan 15 2
60 29254044 pH-responsive selenium nanoparticles stabilized by folate-chitosan delivering doxorubicin for overcoming drug-resistant cancer cells. 2018 Feb 1 1
61 29458045 Aldose reductase inhibitor, fidarestat prevents doxorubicin-induced endothelial cell death and dysfunction. 2018 Apr 1
62 29494960 Prevention of doxorubicin (DOX)-induced genotoxicity and cardiotoxicity: Effect of plant derived small molecule indole-3-carbinol (I3C) on oxidative stress and inflammation. 2018 May 1
63 29655913 Germacrone reverses adriamycin resistance in human chronic myelogenous leukemia K562/ADM cells by suppressing MDR1 gene/P-glycoprotein expression. 2018 May 25 1
64 29749767 Design, synthesis and biological evaluation of some novel quinazolinone derivatives as potent apoptotic inducers. 2018 May 1 1
65 29914576 Effect of β-Eudesmol on NQO1 suppression-enhanced sensitivity of cholangiocarcinoma cells to chemotherapeutic agents. 2018 Jun 19 1
66 29959912 SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling. 2018 Sep 15 1
67 30181466 DOX-Vit D, a Novel Doxorubicin Delivery Approach, Inhibits Human Osteosarcoma Cell Proliferation by Inducing Apoptosis While Inhibiting Akt and mTOR Signaling Pathways. 2018 Sep 4 1
68 30217455 4-Hydroxybenzoic acid (4-HBA) enhances the sensitivity of human breast cancer cells to adriamycin as a specific HDAC6 inhibitor by promoting HIPK2/p53 pathway. 2018 Oct 12 1
69 30266241 Efficacy of metformin in mediating cellular uptake and inducing apoptosis activity of doxorubicin. 2018 Nov 1
70 30387987 In Situ Proapoptotic Peptide-Generating Rapeseed Protein-Based Nanocomplexes Synergize Chemotherapy for Cathepsin-B Overexpressing Breast Cancer. 2018 Dec 5 1
71 30388099 Dehydrocostus Lactone Enhances Chemotherapeutic Potential of Doxorubicin in Lung Cancer by Inducing Cell Death and Limiting Metastasis. 2018 Nov 2 1
72 30485942 Tylophorine Abrogates G2/M Arrest Induced by Doxorubicine and Promotes Increased Apoptosis in T47D Breast Cancer Cells 2018 Nov 29 3
73 33418833 3D Bioprinting of Breast Cancer Models for Drug Resistance Study. 2018 Dec 10 1
74 27863037 Multivalent Aptamer-RNA Conjugates for Simple and Efficient Delivery of Doxorubicin/siRNA into Multidrug-Resistant Cells. 2017 Apr 1
75 28222632 Cryptotanshinone potentiates the antitumor effects of doxorubicin on gastric cancer cells via inhibition of STAT3 activity. 2017 Feb 1
76 28314260 Induction of Apoptosis in Human Oral Keratinocyte by Doxorubicin. 2017 Mar 1
77 28476801 Azacytidine-induced Chemosensitivity to Doxorubicin in Human Breast Cancer MCF7 Cells. 2017 May 2
78 28498322 Valproic Acid Induces Endocytosis-Mediated Doxorubicin Internalization and Shows Synergistic Cytotoxic Effects in Hepatocellular Carcinoma Cells. 2017 May 12 1
79 28627658 Shikonin promotes adriamycin‑induced apoptosis by upregulating caspase‑3 and caspase‑8 in osteosarcoma. 2017 Aug 1
80 28666101 NIR-triggered high-efficient photodynamic and chemo-cascade therapy using caspase-3 responsive functionalized upconversion nanoparticles. 2017 Oct 3
81 28844998 [Effects of bufalin combined with doxorubicin on the proliferation and apoptosis of human lung cancer cell line A549 in vitro]. 2017 Jul 28 2
82 28955990 Synergistic effects of 15-deoxy Δ12,14-prostaglandin J2 on the anti-tumor activity of doxorubicin in renal cell carcinoma. 2017 Mar 1
83 28971453 Gold Rods Irradiated with Ultrasound for Combination of Hyperthermia and Cancer Chemotherapy. 2017 3
84 29098037 Role of cytochrome P450 2J2 on cell proliferation and resistance to an anticancer agent in hepatocellular carcinoma HepG2 cells. 2017 Nov 1
85 29113274 Simvastatin potentiates doxorubicin activity against MCF-7 breast cancer cells. 2017 Nov 1
86 26426519 Protective effects of taurine on doxorubicin-induced acute hepatotoxicity through suppression of oxidative stress and apoptotic responses. 2016 Jan 2
87 26505786 Combinatorial Effects of Curcumin with an Anti-Neoplastic Agent on Head and Neck Squamous Cell Carcinoma Through the Regulation of EGFR-ERK1/2 and Apoptotic Signaling Pathways. 2016 Jan 11 1
88 26520467 Assessment of pro-apoptotic activity of doxorubicin-transferrin conjugate in cells derived from human solid tumors. 2016 Jan 1
89 26525975 Synergic Effects of Doxorubicin and Melatonin on Apoptosis and Mitochondrial Oxidative Stress in MCF-7 Breast Cancer Cells: Involvement of TRPV1 Channels. 2016 Apr 1
90 26590797 Modulation of DNA damage response and induction of apoptosis mediates synergism between doxorubicin and a new imidazopyridine derivative in breast and lung cancer cells. 2016 Jan 1
91 26757339 Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity. 2016 Mar 1
92 26987078 Effect of recombinant human erythropoietin and doxorubicin in combination on the proliferation of MCF-7 and MDA-MB231 breast cancer cells. 2016 May 2
93 27154500 Synthesis of intracellular reduction-sensitive amphiphilic polyethyleneimine and poly(ε-caprolactone) graft copolymer for on-demand release of doxorubicin and p53 plasmid DNA. 2016 Jul 15 1
94 27278553 Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines. 2016 Aug 1
95 27286189 Doxorubicin/heparin composite nanoparticles for caspase-activated prodrug chemotherapy. 2016 Sep 6
96 27487838 Doxorubicin impairs cardiomyocyte viability by suppressing transcription factor EB expression and disrupting autophagy. 2016 Nov 1 3
97 27491234 [Inhibition of Combination of Icaritin and Doxorubicin on Human Osteosarcoma MG-63 Cells in vitro]. 2016 Jun 2
98 27654264 Valproic Acid as a Promising Co-Treatment With Paclitaxel and Doxorubicin in Different Ovarian Carcinoma Cell Lines. 2016 Nov 1
99 27698706 Sulfated polysaccharide-protein complex sensitizes doxorubicin-induced apoptosis of breast cancer cells in vitro and in vivo. 2016 Oct 1
100 27900057 In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism. 2016 Nov 1