Doxorubicin

caspase 3 ; Homo sapiens







224 Article(s)
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201 12743603 Caspase inhibition switches doxorubicin-induced apoptosis to senescence. 2003 May 8 1
202 12899928 Reactive oxygen species mediate doxorubicin induced p53-independent apoptosis. 2003 Sep 5 2
203 14567645 Evaluation of an aerosolized selective COX-2 inhibitor as a potentiator of doxorubicin in a non-small-cell lung cancer cell line. 2003 Sep 2
204 11956583 Human breast cancer MCF-7 cell line contains inherently drug-resistant subclones with distinct genotypic and phenotypic features. 2002 May 2
205 12140766 Proteinase-3, a serine protease which mediates doxorubicin-induced apoptosis in the HL-60 leukemia cell line, is downregulated in its doxorubicin-resistant variant. 2002 Aug 1 1
206 12203125 Doxorubicin-induced death in neuroblastoma does not involve death receptors in S-type cells and is caspase-independent in N-type cells. 2002 Sep 5 1
207 12483536 Down-regulation of caspase 3 in breast cancer: a possible mechanism for chemoresistance. 2002 Dec 12 2
208 11196185 Reconstitution of caspase 3 sensitizes MCF-7 breast cancer cells to doxorubicin- and etoposide-induced apoptosis. 2001 Jan 1 1
209 11289134 Selective sensitization of retinoblastoma protein-deficient sarcoma cells to doxorubicin by flavopiridol-mediated inhibition of cyclin-dependent kinase 2 kinase activity. 2001 Mar 15 1
210 11509031 Zinc inhibition of caspase-3 activation does not protect HeLa cells from apoptotic cell death. 2001 Aug 15 3
211 11572767 Augmented adriamycin sensitivity in cells transduced with an antisense tumor necrosis factor gene is mediated by caspase-3 downstream from reactive oxygen species. 2001 Sep 2
212 10561081 Modulation of CPP32 activity and induction of apoptosis in Human CEM X 174 lymphocytes by heptachlor, a chlorinated hydrocarbon insecticide. 2000 2
213 10766178 Anthracyclines trigger apoptosis of both G0-G1 and cycling peripheral blood lymphocytes and induce massive deletion of mature T and B cells. 2000 Apr 1 1
214 10912804 Doxorubicin treatment activates a Z-VAD-sensitive caspase, which causes deltapsim loss, caspase-9 activity, and apoptosis in Jurkat cells. 2000 Jul 10 1
215 9973225 Chemotherapy augments TRAIL-induced apoptosis in breast cell lines. 1999 Feb 1 2
216 10080945 STAT-1-independent upregulation of FADD and procaspase-3 and -8 in cancer cells treated with cytotoxic drugs. 1999 Mar 24 1
217 10463600 Ku autoantigen affects the susceptibility to anticancer drugs. 1999 Aug 15 1
218 10489162 Differences in apoptosis induced by anticancer drugs in sublines (SKG-3a, SKG-3b) from a human uterine cervical epidermoid carcinoma. 1999 1
219 10582694 Phosphoinositide 3-hydroxide kinase blockade enhances apoptosis in the Ewing's sarcoma family of tumors. 1999 Nov 15 3
220 9642215 Abrogation of mitochondrial cytochrome c release and caspase-3 activation in acquired multidrug resistance. 1998 Jul 3 1
221 9734474 Regulation of cardiomyocyte apoptotic signaling by insulin-like growth factor I. 1998 Sep 7 2
222 9756937 Requirement of caspase-3(-like) protease-mediated hydrogen peroxide production for apoptosis induced by various anticancer drugs. 1998 Oct 9 1
223 9766678 Molecular ordering of apoptosis induced by anticancer drugs in neuroblastoma cells. 1998 Oct 1 1
224 9409752 Doxorubicin-induced apoptosis in human T-cell leukemia is mediated by caspase-3 activation in a Fas-independent way. 1997 Nov 17 2