Title : The carotenoid fucoxanthin can sensitize multidrug resistant cancer cells to doxorubicin via induction of apoptosis, inhibition of multidrug resistance proteins and metabolic enzymes.

Pub. Date : 2020 Oct

PMID : 32712543






1 Functional Relationships(s)
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1 The FUC and DOX combination increased the levels and activity of caspases (CASP3, CASP8) and p53, while decreased the levels and activity of CYP3A4, GST, and PXR in resistant cancer cells. Doxorubicin caspase 3 Homo sapiens