Title : Novel in vivo potential of trifluoperazine to ameliorate doxorubicin-induced cardiotoxicity involves suppression of NF-κB and apoptosis.

Pub. Date : 2021 Oct 15

PMID : 34343539

1 Functional Relationships(s)
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Protein Name
1 Of note, doxorubicin induced the expression of myocardial nuclear NF-kappaB-p65 and caspase-3 which were markedly inhibited by trifluoperazine, suggesting that cardioprotection conferred by trifluoperazine involved, at least in part, suppression of NF-kappaB and apoptosis. Doxorubicin caspase 3 Homo sapiens