Title : Caspase-3-mediated GSDME induced Pyroptosis in breast cancer cells through the ROS/JNK signalling pathway.

Pub. Date : 2021 Sep

PMID : 34369076






2 Functional Relationships(s)
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1 Furthermore, DOX treatments induced intracellular accumulation of ROS, stimulated the phosphorylation of JNK, and Caspase-3 activation, subsequently. Doxorubicin caspase 3 Homo sapiens
2 In conclusion, the study suggests that GSDME triggered DOX-induced pyroptosis in the caspase-3 dependent reactions through the ROS/JNK signalling pathway. Doxorubicin caspase 3 Homo sapiens