Title : Prophylactic, single-drug cardioprotection in a comparative, experimental study of doxorubicin-induced cardiomyopathy.

Pub. Date : 2020 Dec 9

PMID : 33298102






1 Functional Relationships(s)
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1 A decreased number of apoptotic nuclei and a preserved myocardial ultrastructure were found in all groups receiving prophylactic cardioprotection, while the DOX-induced fibrotic remodelling and the increase in caspase-3 levels could only be substantially prevented by the BB and ACEI treatments. Doxorubicin caspase 3 Homo sapiens