Title : Resveratrol potentially increased the tumoricidal effect of doxorubicin on SKOV3 cancer stem cells in vitro.

Pub. Date : 2019 Jan 4

PMID : 30609135

1 Functional Relationships(s)
Compound Name
Protein Name
1 The results of the present study demonstrated that treatment of SKOV3 with 55 muM of RES and 250 nM of DOX simultaneously increased cell viability in CSCs to DOX after 24 and 48 hours by increasing the expression of Bcl-2-associated X protein (BAX) and caspase-3 genes, and decreased the expression and function of multidrug resistance protein 1 (MDR1) and multidrug resistance-associated protein 1 (MRP1) genes indicated by intracellular the rhodamine 123 content. Doxorubicin caspase 3 Homo sapiens