Tyrosine

protein tyrosine phosphatase non-receptor type 6 ; Homo sapiens







150 Article(s)
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1 35559188 Inhibition of SHP2 and SHP1 Protein Tyrosine Phosphatase Activity by Chemically Induced Dimerization. 2022 Apr 26 1
2 33781765 Determination of the molecular reach of the protein tyrosine phosphatase SHP-1. 2021 May 18 1
3 33969922 A possible way to prevent the progression of bone lesions in multiple myeloma via Src-homology-region-2-domain-containing-phosphatase-1 activation. 2021 Oct 1
4 31561841 Regulation of peripheral and central immunity: Understanding the role of Src homology 2 domain-containing tyrosine phosphatases, SHP-1 & SHP-2. 2020 Jan 1
5 31678681 TCDD-mediated suppression of naïve human B cell IgM secretion involves aryl hydrocarbon receptor-mediated reduction in STAT3 serine 727 phosphorylation and is restored by interferon-γ. 2020 Jan 2
6 32152949 Siglecs that Associate with DAP12. 2020 2
7 30951721 A synthetic peptide disturbing GluN2A/SHP1 interaction in dorsal root ganglion attenuated pathological pain. 2019 Jul 5 1
8 31308061 Loss of Function of DOCK4 in Myelodysplastic Syndromes Stem Cells is Restored by Inhibitors of DOCK4 Signaling Networks. 2019 Sep 15 2
9 31679194 TAOK3, a Regulator of LCK-SHP-1 Crosstalk during TCR Signaling. 2019 1
10 30261753 Novel imidazopyridine suppresses STAT3 activation by targeting SHP-1. 2018 Dec 1
11 27959415 Promoter methylation attenuates SHP1 expression and function in patients with primary central nervous system lymphoma. 2017 Feb 1
12 28332308 CEACAM1 long isoform has opposite effects on the growth of human mastocytosis and medullary thyroid carcinoma cells. 2017 Apr 1
13 28619847 Targeted activation of the SHP-1/PP2A signaling axis elicits apoptosis of chronic lymphocytic leukemia cells. 2017 Aug 1
14 26508024 Epigenetic regulation and anti-tumorigenic effects of SH2-containing protein tyrosine phosphatase 1 (SHP1) in human gastric cancer cells. 2016 Apr 2
15 25619838 SHP-1 is a negative regulator of epithelial-mesenchymal transition in hepatocellular carcinoma. 2015 Oct 8 1
16 25730798 An extract of Perilla stem inhibits Src homology phosphatase-1 (SHP)-1 and influences insulin signaling. 2015 Mar 3
17 25833812 Reversal of Arthritis by Human Monomeric IgA Through the Receptor-Mediated SH2 Domain-Containing Phosphatase 1 Inhibitory Pathway. 2015 Jul 2
18 24587194 Regulation of hERG and hEAG channels by Src and by SHP-1 tyrosine phosphatase via an ITIM region in the cyclic nucleotide binding domain. 2014 3
19 24886428 A PKC-SHP1 signaling axis desensitizes Fcγ receptor signaling by reducing the tyrosine phosphorylation of CBL and regulates FcγR mediated phagocytosis. 2014 May 7 1
20 25061875 Shifting FcγRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis. 2014 Sep 1
21 23509253 FCRL5 exerts binary and compartment-specific influence on innate-like B-cell receptor signaling. 2013 Apr 2 1
22 22537350 Functional requirements for inhibitory signal transmission by the immunomodulatory receptor CD300a. 2012 Apr 26 1
23 22960265 SHP-1 protein tyrosine phosphatase associates with the adaptor protein CrkL. 2012 Dec 1
24 20840866 SHP-1 inhibits β-catenin function by inducing its degradation and interfering with its association with TATA-binding protein. 2011 Jan 3
25 21123182 Identification of new substrates of the protein-tyrosine phosphatase PTP1B by Bayesian integration of proteome evidence. 2011 Feb 11 1
26 21799016 Src homology domain 2-containing protein-tyrosine phosphatase-1 (SHP-1) binds and dephosphorylates G(alpha)-interacting, vesicle-associated protein (GIV)/Girdin and attenuates the GIV-phosphatidylinositol 3-kinase (PI3K)-Akt signaling pathway. 2011 Sep 16 4
27 20043942 Identification of key cytosolic kinases containing evolutionarily conserved kinase tyrosine-based inhibitory motifs (KTIMs). 2010 May 1
28 20398180 Calpain-dependent cleavage of SHP-1 and SHP-2 is involved in the dephosphorylation of Jurkat T cells induced by Entamoeba histolytica. 2010 Mar 1
29 20424160 The tyrosine 343 residue of nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) is important for its interaction with SHP1, a cytoplasmic tyrosine phosphatase with tumor suppressor functions. 2010 Jun 25 8
30 19290926 The tyrosine kinase network regulating mast cell activation. 2009 Mar 1
31 19463892 NO-mediated activation of Src kinase during hypoxia in the cerebral cortex of newborn piglets. 2009 Aug 21 1
32 19497338 Insulin induced phosphorylation of prohibitin at tyrosine 114 recruits Shp1. 2009 Aug 3
33 19542910 Siglec-9 and SHP-1 are differentially expressed in neonatal and adult neutrophils. 2009 Sep 1
34 19594633 CD22 and Siglec-G: B-cell inhibitory receptors with distinct functions. 2009 Jul 1
35 20196786 Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling. 2009 Sep 1
36 18024433 Novel binding site for Src homology 2-containing protein-tyrosine phosphatase-1 in CD22 activated by B lymphocyte stimulation with antigen. 2008 Jan 18 15
37 18086677 Dynamic regulation of neutrophil survival through tyrosine phosphorylation or dephosphorylation of caspase-8. 2008 Feb 29 2
38 18377662 Src homology 2 (SH2) domain containing protein tyrosine phosphatase-1 (SHP-1) dephosphorylates VEGF Receptor-2 and attenuates endothelial DNA synthesis, but not migration*. 2008 Mar 31 4
39 18617527 Activation of Cdk2 stimulates proteasome-dependent truncation of tyrosine phosphatase SHP-1 in human proliferating intestinal epithelial cells. 2008 Sep 12 2
40 17046078 Late signaling in the activated platelets upregulates tyrosine phosphatase SHP1 and impairs platelet adhesive functions: Regulation by calcium and Src kinase. 2007 Feb 1
41 17404032 SHP-1 tyrosine phosphatase in human erythrocytes. 2007 Jan 4
42 17522256 Fc receptor-like 5 inhibits B cell activation via SHP-1 tyrosine phosphatase recruitment. 2007 Jun 5 1
43 17558712 Vanadate-induced inhibition of BCR-triggered apoptosis is coupled with tyrosine phosphorylation and induction of G2M growth arrest in Ramos-BL B cells. 2007 1
44 17575265 Rapid T cell receptor-mediated SHP-1 S591 phosphorylation regulates SHP-1 cellular localization and phosphatase activity. 2007 Sep 1
45 17579069 Identification of a novel lipid raft-targeting motif in Src homology 2-containing phosphatase 1. 2007 Jul 1 1
46 17892531 hTRPC1-associated alpha-actinin, and not hTRPC1 itself, is tyrosine phosphorylated during human platelet activation. 2007 Dec 1
47 16360206 Granulocyte macrophage-colony stimulating factor reduces the affinity of SHP-2 for the ITIM of CLECSF6 in neutrophils: a new mechanism of action for SHP-2. 2006 Apr 1
48 16581823 A novel avian homologue of CD72, chB1r, down modulates BCR-mediated activation signals. 2006 May 1
49 16702225 Sequence specificity of SHP-1 and SHP-2 Src homology 2 domains. Critical roles of residues beyond the pY+3 position. 2006 Jul 21 1
50 16762922 Antagonism or synergism. Role of tyrosine phosphatases SHP-1 and SHP-2 in growth factor signaling. 2006 Aug 4 1