Title : Fc receptor-like 5 inhibits B cell activation via SHP-1 tyrosine phosphatase recruitment.

Pub. Date : 2007 Jun 5

PMID : 17522256






1 Functional Relationships(s)
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1 This FCRL5 inhibitory effect was mediated through dual ITIM recruitment of the SH2-containing protein tyrosine phosphatase, SHP-1, which in turn dephosphorylates the ITAM-based tyrosines in BCR Igalpha/Igbeta heterodimers. Tyrosine protein tyrosine phosphatase non-receptor type 6 Homo sapiens