Title : Activation of Cdk2 stimulates proteasome-dependent truncation of tyrosine phosphatase SHP-1 in human proliferating intestinal epithelial cells.

Pub. Date : 2008 Sep 12

PMID : 18617527






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mutational analysis of Tyr(208) and Ser(591) (a Cdk2 phosphorylation site) residues on SHP-1 abolished the expression of the amino-truncated 45-kDa SHP-1 protein. Tyrosine protein tyrosine phosphatase non-receptor type 6 Homo sapiens
2 Mutational analysis of Tyr(208) and Ser(591) (a Cdk2 phosphorylation site) residues on SHP-1 abolished the expression of the amino-truncated 45-kDa SHP-1 protein. Tyrosine protein tyrosine phosphatase non-receptor type 6 Homo sapiens