Tyrosine

protein tyrosine phosphatase non-receptor type 6 ; Homo sapiens







150 Article(s)
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51 16825495 Loss of SHP1 enhances JAK3/STAT3 signaling and decreases proteosome degradation of JAK3 and NPM-ALK in ALK+ anaplastic large-cell lymphoma. 2006 Oct 15 1
52 16871283 Restoration of shp1 expression by 5-AZA-2'-deoxycytidine is associated with downregulation of JAK3/STAT3 signaling in ALK-positive anaplastic large cell lymphoma. 2006 Sep 1
53 16898954 Platelet nitric oxide synthase is activated by tyrosine dephosphorylation: possible role for SHP-1 phosphatase. 2006 Nov 1
54 15886119 The role of CD22 and other inhibitory co-receptors in B-cell activation. 2005 Jun 1
55 15893190 The tyrosine phosphatase, SHP-1, is a negative regulator of endothelial superoxide formation. 2005 May 17 2
56 15987791 Protein tyrosine phosphatase kappa and SHP-1 are involved in the regulation of cell-cell contacts at adherens junctions in the exocrine pancreas. 2005 Oct 2
57 16339585 Expression and activity of NOX5 in the circulating malignant B cells of hairy cell leukemia. 2005 Dec 15 1
58 14672952 PTPH1 is a predominant protein-tyrosine phosphatase capable of interacting with and dephosphorylating the T cell receptor zeta subunit. 2004 Feb 27 1
59 14732700 Ly49Q, a member of the Ly49 family that is selectively expressed on myeloid lineage cells and involved in regulation of cytoskeletal architecture. 2004 Jan 27 1
60 15187115 KIR2DL5 can inhibit human NK cell activation via recruitment of Src homology region 2-containing protein tyrosine phosphatase-2 (SHP-2). 2004 Jun 15 1
61 15240681 SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation. 2004 Jul 15 1
62 15269224 Regulation of SHP-1 tyrosine phosphatase in human platelets by serine phosphorylation at its C terminus. 2004 Sep 24 4
63 12459556 Regulation of the dephosphorylation of Stat6. Participation of Tyr-713 in the interleukin-4 receptor alpha, the tyrosine phosphatase SHP-1, and the proteasome. 2003 Feb 7 4
64 12468540 The role of C-terminal tyrosine phosphorylation in the regulation of SHP-1 explored via expressed protein ligation. 2003 Feb 14 6
65 12707331 Src homology region 2-containing protein tyrosine phosphatase-2 (SHP-2) can play a direct role in the inhibitory function of killer cell Ig-like receptors in human NK cells. 2003 May 1 1
66 11831857 Regulation of postaggregation events induced by protease-activated receptor 1 ligation in human platelets: evidence of differential signaling pathways. 2002 Feb 15 3
67 11907066 Cutting edge: differential segregation of the SRC homology 2-containing protein tyrosine phosphatase-1 within the early NK cell immune synapse distinguishes noncytolytic from cytolytic interactions. 2002 Apr 1 1
68 11986327 Cloning and characterization of human Siglec-11. A recently evolved signaling molecule that can interact with SHP-1 and SHP-2 and is expressed by tissue macrophages, including brain microglia. 2002 Jul 5 1
69 11994426 The ligand-binding domain of CD22 is needed for inhibition of the B cell receptor signal, as demonstrated by a novel human CD22-specific inhibitor compound. 2002 May 6 1
70 11994457 SHP-1- and phosphotyrosine-independent inhibitory signaling by a killer cell Ig-like receptor cytoplasmic domain in human NK cells. 2002 May 15 1
71 12051764 SPAP2, an Ig family receptor containing both ITIMs and ITAMs. 2002 May 10 2
72 12145285 SHP1 protein-tyrosine phosphatase regulates HoxA10 DNA binding and transcriptional repression activity in undifferentiated myeloid cells. 2002 Sep 27 2
73 12361947 Modulation of the ERG K+ current by the tyrosine phosphatase, SHP-1. 2002 Dec 13 2
74 11162587 Molecular cloning and characterization of SPAP1, an inhibitory receptor. 2001 Jan 26 1
75 11238643 Targeting Src homology 2 domain-containing tyrosine phosphatase (SHP-1) into lipid rafts inhibits CD3-induced T cell activation. 2001 Mar 15 1
76 11328818 Identification and characterization of S2V, a novel putative siglec that contains two V set Ig-like domains and recruits protein-tyrosine phosphatases SHPs. 2001 Jun 29 1
77 11337495 Tyrosine phosphorylation of p85 relieves its inhibitory activity on phosphatidylinositol 3-kinase. 2001 Jul 20 1
78 11513144 Inhibition of natural killer cell activation signals by killer cell immunoglobulin-like receptors (CD158). 2001 Jun 2
79 11544253 G6b, a novel immunoglobulin superfamily member encoded in the human major histocompatibility complex, interacts with SHP-1 and SHP-2. 2001 Nov 9 1
80 11733002 A new siglec family member, siglec-10, is expressed in cells of the immune system and has signaling properties similar to CD33. 2001 Dec 1
81 10623804 Effects of Src homology domain 2 (SH2)-containing inositol phosphatase (SHIP), SH2-containing phosphotyrosine phosphatase (SHP)-1, and SHP-2 SH2 decoy proteins on Fc gamma RIIB1-effector interactions and inhibitory functions. 2000 Jan 15 1
82 10658974 NK cell activation: distinct stimulatory pathways counterbalancing inhibitory signals. 2000 Jan 1
83 10660620 PILRalpha, a novel immunoreceptor tyrosine-based inhibitory motif-bearing protein, recruits SHP-1 upon tyrosine phosphorylation and is paired with the truncated counterpart PILRbeta. 2000 Feb 11 7
84 10764762 Identification and characterization of leukocyte-associated Ig-like receptor-1 as a major anchor protein of tyrosine phosphatase SHP-1 in hematopoietic cells. 2000 Jun 9 6
85 10772872 SH2-Containing protein tyrosine phosphatase-1 (SHP-1) association with Jak2 in UT-7/Epo cells. 2000 Feb 1
86 10835420 The protein-tyrosine phosphatase SHP-1 binds to and dephosphorylates p120 catenin. 2000 Aug 25 4
87 10849365 Recruitment of SHP-1 protein tyrosine phosphatase and signalling by a chimeric T-cell receptor-killer inhibitory receptor. 2000 Jun 1
88 10887109 Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2. 2000 Jul 15 2
89 10898979 Adhesion to target cells is disrupted by the killer cell inhibitory receptor. 2000 Jun 29 1
90 11035084 Mutational analysis reveals multiple distinct sites within Fc gamma receptor IIB that function in inhibitory signaling. 2000 Oct 15 1
91 9867848 The carboxyl-terminal region of biliary glycoprotein controls its tyrosine phosphorylation and association with protein-tyrosine phosphatases SHP-1 and SHP-2 in epithelial cells. 1999 Jan 1 1
92 9890995 Definition of the sites of interaction between the protein tyrosine phosphatase SHP-1 and CD22. 1999 Jan 22 1
93 9916713 Conserved residues amino-terminal of cytoplasmic tyrosines contribute to the SHP-1-mediated inhibitory function of killer cell Ig-like receptors. 1999 Jan 15 2
94 10082557 CD5 negatively regulates the T-cell antigen receptor signal transduction pathway: involvement of SH2-containing phosphotyrosine phosphatase SHP-1. 1999 Apr 3
95 10206955 The myeloid-specific sialic acid-binding receptor, CD33, associates with the protein-tyrosine phosphatases, SHP-1 and SHP-2. 1999 Apr 23 6
96 10228003 CD45 regulates tyrosine phosphorylation of CD22 and its association with the protein tyrosine phosphatase SHP-1. 1999 May 1 3
97 10350061 Differential association of cytoplasmic signalling molecules SHP-1, SHP-2, SHIP and phospholipase C-gamma1 with PECAM-1/CD31. 1999 Apr 30 2
98 10358776 Regulation of immune responses through inhibitory receptors. 1999 1
99 10395658 A new role for platelet-endothelial cell adhesion molecule-1 (CD31): inhibition of TCR-mediated signal transduction. 1999 Jul 15 1
100 10399074 Human cytomegalovirus, MHC class I and inhibitory signalling receptors: more questions than answers. 1999 Apr 1